ArticleThe Pediatric infectious disease journal2015
Epidemiology and virology of acute respiratory infections during the first year of life: a birth cohort study in Vietnam.
Article in The Pediatric infectious disease journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- A Systematic Review of the Markers of Severity in Acute Respiratory Infections to Inform Primary Care Surveillance.Influenza and other respiratory viruses · 2025Pooled it
- Respiratory syncytial virus in the Western Pacific Region: a systematic review and meta-analysis.Journal of global health · 2019Pooled it
- Burden of Respiratory Viruses in Children Less Than 2 Years Old in a Community-based Longitudinal US Birth Cohort.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Estimating the economic burden of respiratory syncytial virus infections in infants in Vietnam: a cohort study.BMC infectious diseases · 2023Article
- Article
- Prevalence of respiratory viruses among paediatric patients in acute respiratory illnesses in Malaysia.PloS one · 2022Article
- Interactions of genetic variants and prenatal stress in relation to the risk for recurrent respiratory infections in children.Scientific reports · 2021Article
- The incidence of acute respiratory infection in Indonesian infants and association with vitamin D deficiency.PloS one · 2021Article
- Changing Epidemiology of Acute Respiratory Infections in Under-Two Children in Dhaka, Bangladesh.Frontiers in pediatrics · 2021Article
- Circulation profile of respiratory viruses in symptomatic and asymptomatic children from Midwest Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- Respiratory viruses in individuals with a high frequency of animal exposure in southern and highland Vietnam.Journal of medical virology · 2020Article
- Epidemiology and Phylogenetic Analysis of Viral Respiratory Infections in Vietnam.Frontiers in microbiology · 2020Article
- Age-specific incidence rates and risk factors for respiratory syncytial virus-associated lower respiratory tract illness in cohort children under 5 years old in the Philippines.Influenza and other respiratory viruses · 2019Article
- Burden, Etiology, and Risk Factors of Respiratory Virus Infections Among Symptomatic Preterm Infants in the Tropics: A Retrospective Single-Center Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Primary care influenza-like illness surveillance in Ho Chi Minh City, Vietnam 2013-2015.Influenza and other respiratory viruses · 2018Observational
- Observational
- Article
- Parents' depression and loneliness during pregnancy and respiratory infections in the offspring: A prospective birth cohort study.PloS one · 2018Article
- Population-Based Pediatric Hospitalization Burden of Lineage-Specific Influenza B in Hong Kong, 2004-2014.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Exposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundUnderstanding viral etiology and age-specific incidence of acute respiratory infections in infants can help identify risk groups and inform vaccine delivery, but community-based data is lacking from tropical settings.
methodsOne thousand four hundred and seventy-eight infants in urban Ho Chi Minh City and 981 infants in a semi-rural district in southern Vietnam were enrolled at birth and followed to 1 year of age. Acute respiratory infection (ARI) episodes were identified through clinic-based illness surveillance, hospital admissions and self-reports. Nasopharyngeal swabs were collected from infants with respiratory symptoms and tested for 14 respiratory pathogens using multiplex reverse transcription-polymerase chain reaction.
resultsEstimated incidence of ARI was 542 and 2691 per 1000 infant-years, and hospitalization rates for ARI were 81 and 138 per 1000 infant-years, in urban and semi-rural cohorts, respectively, from clinic- and hospital-based surveillance. However self-reported ARI episodes were just 1.5-fold higher in the semi-rural versus urban cohort, indicating that part of the urban-rural difference was explained by under-ascertainment in the urban cohort. Incidence was higher in infants ≥6 months of age than <6 months, but this was pathogen-specific. One or more viruses were detected in 53% (urban) and 64% (semi-rural) of samples from outpatients with ARI and in 78% and 66% of samples from hospitalized ARI patients, respectively. The most frequently detected viruses were rhinovirus, respiratory syncytial virus, influenza virus A and bocavirus. ARI-associated hospitalizations were associated with longer stays and more frequent ICU admission than other infections.
conclusionsARI is a significant cause of morbidity in Vietnamese infants and influenza virus A is an under-appreciated cause of vaccine-preventable disease and hospitalizations in this tropical setting. Public health strategies to reduce infant ARI incidence and hospitalization rates are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.