Evidence map›Paper›PMID 25674515›Full record

ReviewWorld journal of virology2015

Current molecular methods for the detection of hepatitis C virus in high risk group population: A systematic review.

Rushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan

Abstract readReview
In one paragraph

Review in World journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. A review of historical landmarks and pioneering technologies for the diagnosis of Hepatitis C Virus (HCV).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
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  14. Update on hepatitis B and C virus diagnosis.World journal of virology · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rushna FirdausRushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan, ICMR Virus Unit, I.D and B.G Hospital Campus, GB-4 (East Wing), Beliaghata, Kolkata 700010, India.
Kallol SahaRushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan, ICMR Virus Unit, I.D and B.G Hospital Campus, GB-4 (East Wing), Beliaghata, Kolkata 700010, India.
Aritra BiswasRushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan, ICMR Virus Unit, I.D and B.G Hospital Campus, GB-4 (East Wing), Beliaghata, Kolkata 700010, India.
Provash Chandra SadhukhanRushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan, ICMR Virus Unit, I.D and B.G Hospital Campus, GB-4 (East Wing), Beliaghata, Kolkata 700010, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) is an emerging infection worldwide and the numbers of persons infected are increasing every year. Poor blood transfusion methods along with unsafe injection practices are potential sources for the rapid spread of infection. Early detection of HCV is the need of the hour especially in high risk group population as these individuals are severely immunocompromised. Enzyme Immunoassays are the most common detection techniques but they provide no evidence of active viremia or identification of infected individuals in the antibody-negative phase and their efficacy is limited in individuals within high risk group population. Molecular virological techniques have an important role in detecting active infection with utmost specificity and sensitivity. Technologies for assessment of HCV antibody and RNA levels have improved remarkably, as well as our understanding of how to best use these tests in patient management. This review aims to give an overview of the different serological and molecular methods employed in detecting HCV infection used nowadays. Additionally, the review gives an insight in the new molecular techniques that are being developed to improve the detection techniques particularly in High Risk Group population who are severely immunocompromised.

Indexed as

Enzyme immunoassayHigh risk group populationMolecular detectionNucleic acid amplification assaysPolymerase chain reaction

Identifiers

PMID25674515
PMCPMC4308525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.