ArticleSpringerPlus2014
Practice of switch from intravenous to oral antibiotics.
Article in SpringerPlus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07407491 (Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis: A Randomized Controlled Trial
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Does the duration of antibiotic treatment following one-stage treatment of infected total knee arthroplasty influence the eradication rate? A systematic review.Archives of orthopaedic and trauma surgery · 2024Pooled it
- Nurse-Led and Nurse-Involved Antimicrobial Stewardship in Hospitals and Primary Care: Protocol for a Mixed Methods Systematic Review and Meta-Analysis With Gulf Cooperation Council and Middle East and North Africa Subgroup Analysis.JMIR research protocols · 2026Article
- Article
- The effectiveness of intravenous (IV) to oral (PO) antibiotic switch (IVOS) interventions in managing community- and hospital-acquired pneumonia-a systematic review.JAC-antimicrobial resistance · 2026Review
- Antibiotic Use in Pediatric Care in Ghana: A Call to Action for Stewardship in This Population.Antibiotics (Basel, Switzerland) · 2025Article
- Transitioning to oral therapy compared to IV inAnnals of medicine and surgery (2012) · 2025Article
- Analysis of the practice of switch of antibiotics from intravenous to oral therapy at a tertiary care hospital in Nepal: a prospective observational study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Single center, retrospective evaluation of requiring 48 hours versus 24 hours before a pharmacist-driven protocol-based IV to PO conversion of azithromycin.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Antimicrobial use in hospitalized patients: a point prevalence survey across four tertiary hospitals in Niger.JAC-antimicrobial resistance · 2024Article
- Modern Microbiological Methods to Detect Biofilm Formation in Orthopedy and Suggestions for Antibiotic Therapy, with Particular Emphasis on Prosthetic Joint Infection (PJI).Microorganisms · 2024Review
- Physicians' understanding of antibiotic intravenous-to-oral switching-a qualitative study in Suzhou, China.BMC health services research · 2024Article
- Using Culture Sensitivity Reports to Optimize Antimicrobial Therapy: Findings and Implications of Antimicrobial Stewardship Activity in a Hospital in Pakistan.Medicina (Kaunas, Lithuania) · 2023Observational
- No more tears from surgical site infections in interventional pain management.The Korean journal of pain · 2023Review
- Opportunities, associations, and impact of early intravenous to oral antimicrobial switch for hospitalized patients in Ethiopia.SAGE open medicine · 2023Article
- Change in the Perception of Oral Antibiotics Among Medical Students After Participating in a Parenteral-to-Oral Conversion Program for Highly Bioavailable Antibiotics.Open forum infectious diseases · 2022Article
- Appropriateness of surgical antimicrobial prophylaxis in a teaching hospital in Ghana: findings and implications.JAC-antimicrobial resistance · 2022Article
- Antimicrobial Utilization among Neonates and Children: A Multicenter Point Prevalence Study from Leading Children's Hospitals in Punjab, Pakistan.Antibiotics (Basel, Switzerland) · 2022Article
- Antibiotic stewardship in the era of precision medicine.JAC-antimicrobial resistance · 2022Review
- Point prevalence study of antibiotic appropriateness and possibility of early discharge from hospital among patients treated with antibiotics in a Swiss University Hospital.Antimicrobial resistance and infection control · 2022Article
- Antibiotic Therapy for Prosthetic Joint Infections: An Overview.Antibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hospitalized patients initially on intravenous antibiotics can be safely switched to an oral equivalent within the third day of admission once clinical stability is established. This conversion has many advantages as fewer complications, less healthcare costs and earlier hospital discharge. The three types of intravenous to oral conversion include sequential, switch, and step-down therapy. The aim of the study was to evaluate the practice of switching from intravenous to oral antibiotics, its types and its impact on the clinical outcomes. This was a retrospective observational study conducted in three Lebanese hospitals over a period of six months. Adult inpatients on intravenous antibiotics for 2 days and more were eligible for study enrollment. Excluded were patients admitted to care or surgery units, or those with gastrointestinal diseases, infections that require prolonged course of parenteral therapy, or malignancies. The study showed that among 452 intravenous antibiotic courses from 356 patients who were eligible for conversion, only one third were switched and the others continued on intravenous antibiotics beyond day 3 (P <0.0001). The mean duration of intravenous therapy of converted patients was markedly shorter than the non-converted (P <0.0001) with no significant change in the mean length of stay. Fluoroquinolones and macrolides were the most commonly converted antibiotics. However, the sequential therapy was the major type of conversion practiced in this study. Based on the study findings, a significant proportion of patients can be considered for switch. This emphasizes an important gap in the field of conversion from intravenous to oral antibiotic therapy and the need for integration and reinforcement of the appropriate Antibiotic Stewardship Programs in hospitals.
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