ArticleJournal of global health2015
Understanding maternal mortality from top-down and bottom-up perspectives: Case of Tigray Region, Ethiopia.
Article in Journal of global health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Maternal mortality in Ethiopia (2015-2025): a systematic review of recent evidence and determinants.BMC public health · 2025Pooled it
- A systematic review of individual and ecological determinants of maternal mortality in the world based on the income level of countries.BMC public health · 2022Pooled it
- Causes of maternal mortality in Sub-Saharan Africa: A systematic review of studies published from 2015 to 2020.Journal of global health · 2021Pooled it
- Delayed initiation of antenatal care and associated factors in Ethiopia: a systematic review and meta-analysis.Reproductive health · 2017Pooled it
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- The impact of comprehensive training on safe cesarean delivery on non-physician surgeons' knowledge in Tigray, Ethiopia: a pre- and post-test embedded mixed-methods study.Human resources for health · 2026Article
- Preconception health risk profiles among women planning pregnancy in northern Ethiopia: a latent class analysis.BMJ open · 2025Article
- Lessons learned from applying a "Rapid Maternal Death Surveillance and Response" tool in conflict-affected Tigray, Ethiopia.BMC pregnancy and childbirth · 2025Article
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- Maternal death surveillance efforts: notification and review coverage rates in 30 low-income and middle-income countries, 2015-2019.BMJ open · 2023Article
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- Time to recovery from Eclampsia and its determinants in east Gojjam zone hospitals, Amhara, Ethiopia, 2017/18.BMC pregnancy and childbirth · 2021Article
- Triangulating data sources for further learning from and about the MDSR in Ethiopia: a cross-sectional review of facility based maternal death data from EmONC assessment and MDSR system.BMC pregnancy and childbirth · 2020Review
- Awareness of pregnancy induced hypertension among pregnant women in Tigray Regional State, Ethiopia.The Pan African medical journal · 2020Article
- Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study.BMC pregnancy and childbirth · 2019Article
- Maternal and perinatal death surveillance and response in Ethiopia: Achievements, challenges and prospects.PloS one · 2019Article
- Magnitude, trends and causes of maternal mortality among reproductive aged women in Kersa health and demographic surveillance system, eastern Ethiopia.BMC women's health · 2018Article
- Predictors of postpartum contraceptive use in rural Tigray region, northern Ethiopia: a multilevel analysis.BMC public health · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnacceptably high levels of preventable maternal mortality persist as a problem across sub-Saharan Africa and much of south Asia. Currently, local assessments of the magnitude of maternal mortality are not often made, so the best available information for health planning may come from global estimates and not reflect local circumstances.
methodsA community-based cross-sectional survey was designed to identify all live births together with all deaths among women aged 15-49 years retrospectively over a one-year period in six randomly selected districts of Tigray Region, northern Ethiopia. After birth and death identification, Health Extension Workers trained to use the WHO 2012 verbal autopsy (VA) tool visited households to carry out VAs on all deaths among women aged 15-49 years. All pregnancy-related deaths were identified after processing the VA material using the InterVA-4 model, which corresponds to the WHO 2012 VA. A maternal mortality ratio (MMR) was calculated for each District and expressed with a 95% confidence interval (CI).
resultsThe MMRs across the six sampled Districts ranged from 37 deaths per 100 000 live births (95% CI 1 to 207) to 482 deaths per 100 000 live births (95% CI 309 to 718). The overall MMR for Tigray Region was calculated at 266 deaths per 100 000 live births (95% CI 198 to 350). Direct obstetric causes accounted for 61% of all pregnancy-related deaths. Haemorrhage was the major cause of pregnancy-related death (34%). District-level MMRs were strongly inversely correlated with population density (r(2) = 0.86).
conclusionThis simple but well-designed survey approach enabled estimation of maternal mortality in Tigray Region on a local, contemporary basis. It also provided insights into possible local variations in MMR and their determinants. Consequently, this approach could be implemented at regional level in other large sub-Saharan African countries, or at national level in smaller ones to monitor and evaluate maternal health service interventions.
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