Evidence map›Paper›PMID 25674222›Full record

ArticleInternational journal of clinical and experimental pathology2014

Proliferation and apoptosis of Peyer's patches and its lymphocytes in experimental terminal ileitis.

Wei Wang, Ailei Xu, Guohua Zhou, Mingfang Leng, Hongyu Zhou, Jun Yan

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wei WangDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Ailei XuDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Guohua ZhouDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Mingfang LengDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Hongyu ZhouDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Jun YanDepartment of Gastroenterology, Affiliated Xiangnan Hospital of Hunan Normal University 169 Hospital of PLA, Hengyang, P.R. China.
Hengyang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study will provide guide for the terminal ileitis in clinical diagnosis and treatment. The animals were been done terminal ileum-cecum side to side anastomosis, terminal ileum operation line and only anesthesia treatment, respectively. The model group presented acute inflammation after surgery for 2 weeks and the inflammation was limited to the mucosal layer. Animals presented chronic inflammation to 8 weeks, mucosal membrane was given priority to with lymphocytic infiltrates. In 2 weeks and 4 weeks, the number of Peyer's patches (PP knot) and PP knot lymphocytes increased significantly in the model group (P < 0.05, P < 0.01). At 8 weeks, the suture group and the model group presented a large number of lymphocytic apoptosis (P < 0.01). Rat ileal PP knot lymphocyte small molecule DNA showed typical "trapezoid" bands. We observed apparent morphology of apoptosis and crescent-shaped nucleus. Continuous immune response in terminal ileitis plays a considerable role in the process of the disease.

Indexed as

AnimalsApoptosisCell ProliferationCrohn DiseaseDisease Models, AnimalLymphocytesMalePeyer's PatchesRatsRats, Sprague-DawleyCell apoptosislymphocytesPP knotterminal ileitis

Identifiers

PMID25674222
PMCPMC4313998
OpenAlexW162792245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.