ReviewFrontiers in immunology2015
The contribution of the maternal immune system to the establishment of pregnancy in cattle.
Review in Frontiers in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 96 citations in OpenAlex.
- Article
- Article
- Article
- Gastrointestinal Parasitism in Cattle and Water Buffaloes in Pakistan: Prevalence and Associated Risk Factors.Acta parasitologica · 2026Article
- Bovine endometrial organoids: a new tool to study conceptus-maternal interactions in mammals†.Biology of reproduction · 2026Article
- Quantitative proteomic profiling of placental extracellular vesicles in recurrent pregnancy loss reveals their role in feto-maternal crosstalk.BMC pregnancy and childbirth · 2026Article
- Regulation of the maternal immune system during early bovine pregnancy.Reproduction & fertility · 2026Review
- Review
- Network-based multi-omics approaches to identify molecular signatures associated with pregnancy status in beef heifers.Frontiers in genetics · 2026Article
- Effects of administration of a non-specific immunostimulant prior to mating on pregnancy establishment and fetal and placental development in mice.Biochemistry and biophysics reports · 2025Article
- Article
- Single-cell sequencing reveals alterations in the ovarian immune microenvironment regulated by 17β-estradiol in neonatal mice.Zoological research · 2025Article
- Impact of Low Inclusion Rate of Olive Cake in Dairy Cow Rations on Uterine Health and Fertility Indices During Early Lactation.Animals : an open access journal from MDPI · 2025Article
- The dominant follicle: the final frontier in bovine oocyte development.Animal reproduction · 2025Article
- Mapping Expression Quantitative Trait Loci Targeting Candidate Genes for Pregnancy in Beef Cows.Biomolecules · 2024Article
- Extensive rewiring of the gene regulatory interactions between in vitro-produced conceptuses and endometrium during attachment.PNAS nexus · 2023Article
- Understanding the underlying genetic mechanisms for age at first calving, inter-calving period and scrotal circumference in Bonsmara cattle.BMC genomics · 2023Article
- Article
- Paternal effects on fetal programming.Animal reproduction · 2023Review
- miRNA expression profiles of peripheral white blood cells from beef heifers with varying reproductive potential.Frontiers in genetics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune cells play an integral role in affecting successful reproductive function. Indeed, disturbed or aberrant immune function has been identified as primary mechanisms behind infertility. In contrast to the extensive body of literature that exists for human and mouse, studies detailing the immunological interaction between the embryo and the maternal endometrium are quite few in cattle. Nevertheless, by reviewing the existing studies and extrapolating from sheep, pig, mouse, and human data, we can draw a reasonably comprehensive picture. Key contributions of immune cell populations include granulocyte involvement in follicle differentiation and gamete transfer, monocyte invasion of the peri-ovulatory follicle and their subsequent role in corpus luteum formation and the pivotal roles of maternal macrophage and dendritic cells in key steps of the establishment of pregnancy, particularly, the maternal immune response to the embryo. These contributions are reviewed in detail below and key findings are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.