ReviewFrontiers in microbiology2015
Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals.
Review in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
55 citing papers in PubMed, 131 citations in OpenAlex.
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- In the battle of survival: transcriptome analysis of hypopharyngeal gland of the Apis mellifera under temperature-stress.BMC genomics · 2025Article
- PxDorsal Regulates the Expression of Antimicrobial Peptides and Affects the Bt Susceptibility ofInsects · 2025Article
- Transcriptomic analysis of Rhipicephalus microplus hemocytes from female ticks infected with Babesia bovis or Babesia bigemina.Parasites & vectors · 2025Article
- MdSVWC1, a new pattern recognition receptor triggers multiple defense mechanisms against invading bacteria in Musca domestica.BMC biology · 2024Article
- Paracoccidioides lutzii Infects Galleria mellonella Employing Formamidase as a Virulence Factor.PLoS neglected tropical diseases · 2024Article
- A novel prolixicin identified in common bed bugs with activity against both bacteria and parasites.Scientific reports · 2024Article
- Activation of immune pathways in common bed bugs,Frontiers in immunology · 2024Article
- AVirulence · 2023Article
- Functional Analysis of a CTL-X-Type Lectin CTL16 in Development and Innate Immunity ofInternational journal of molecular sciences · 2023Article
- Biological Activities and Chemical Profiles ofPlants (Basel, Switzerland) · 2023Article
- Host-pathogen interaction in arthropod vectors: Lessons from viral infections.Frontiers in immunology · 2023Review
- Reference Genome Sequences of the Oriental Armyworm,Insects · 2022Article
- Potential role of prebiotics and probiotics in conferring health benefits in economically important crabs.Fish and shellfish immunology reports · 2022Review
- Gene family expansions in Antarctic winged midge as a strategy for adaptation to cold environments.Scientific reports · 2022Article
- Characterization of New Defensin Antimicrobial Peptides and Their Expression in Bed Bugs in Response to Bacterial Ingestion and Injection.International journal of molecular sciences · 2022Article
- Review
- In Silico Characterization and Gene Expression Analysis of Toll Signaling Pathway-Related Genes inInsects · 2022Article
- Transcriptome analysis of sex-biased gene expression in the spotted-wing Drosophila, Drosophila suzukii (Matsumura).G3 (Bethesda, Md.) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
In response to bacterial and fungal infections in insects and mammals, distinct families of innate immune pattern recognition receptors (PRRs) initiate highly complex intracellular signaling cascades. Those cascades induce a variety of immune functions that restrain the spread of microbes in the host. Insect and mammalian innate immune receptors include molecules that recognize conserved microbial molecular patterns. Innate immune recognition leads to the recruitment of adaptor molecules forming multi-protein complexes that include kinases, transcription factors, and other regulatory molecules. Innate immune signaling cascades induce the expression of genes encoding antimicrobial peptides and other key factors that mount and regulate the immune response against microbial challenge. In this review, we summarize our current understanding of the bacterial and fungal PRRs for homologous innate signaling pathways of insects and mammals in an effort to provide a framework for future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.