ReviewFrontiers in cellular neuroscience2014
Interkinetic nuclear migration generates and opposes ventricular-zone crowding: insight into tissue mechanics.
Review in Frontiers in cellular neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
- Early spinal cord development: from neural tube formation to neurogenesis.Nature reviews. Neuroscience · 2025Review
- Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium.Development, growth & differentiation · 2024Article
- A novel preparation for histological analyses of intraventricular macrophages in the embryonic brain.Development, growth & differentiation · 2024Article
- Temporal morphogen gradient-driven neural induction shapes single expanded neuroepithelium brain organoids with enhanced cortical identity.Nature communications · 2023Article
- A balance of noncanonical Semaphorin signaling from the cerebrospinal fluid regulates apical cell dynamics during corticogenesis.Science advances · 2022Article
- Nuclear movement in multinucleated cells.Development (Cambridge, England) · 2022Review
- Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration.Cell reports · 2022Article
- Mechanical constraints to cell-cycle progression in a pseudostratified epithelium.Current biology : CB · 2022Article
- Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure.Cells · 2021Article
- SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity.The Journal of cell biology · 2021Article
- Primary Cilia and Centrosomes in Neocortex Development.Frontiers in neuroscience · 2021Review
- Epstein-Barr virus-based plasmid enables inheritable transgene expression in mouse cerebral cortex.PloS one · 2021Article
- Autosomal Recessive Primary Microcephaly: Not Just a Small Brain.Frontiers in cell and developmental biology · 2021Review
- Toward Spatial Identities in Human Brain Organoids-on-Chip Induced by Morphogen-Soaked Beads.Bioengineering (Basel, Switzerland) · 2020Article
- RYK-mediated filopodial pathfinding facilitates midgut elongation.Development (Cambridge, England) · 2020Article
- Nuclear crowding and nonlinear diffusion during interkinetic nuclear migration in the zebrafish retina.eLife · 2020Article
- Huntington's disease alters human neurodevelopment.Science (New York, N.Y.) · 2020Article
- Two-photon microscopic observation of cell-production dynamics in the developing mammalian neocortex in utero.Development, growth & differentiation · 2020Article
- Mechanical Regulation of Nuclear Translocation in Migratory Neurons.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neuroepithelium (NE) or ventricular zone (VZ), from which multiple types of brain cells arise, is pseudostratified. In the NE/VZ, neural progenitor cells are elongated along the apicobasal axis, and their nuclei assume different apicobasal positions. These nuclei move in a cell cycle-dependent manner, i.e., apicalward during G2 phase and basalward during G1 phase, a process called interkinetic nuclear migration (INM). This review will summarize and discuss several topics: the nature of the INM exhibited by neural progenitor cells, the mechanical difficulties associated with INM in the developing cerebral cortex, the community-level mechanisms underlying collective and efficient INM, the impact on overall brain formation when NE/VZ is overcrowded due to loss of INM, and whether and how neural progenitor INM varies among mammalian species. These discussions will be based on recent findings obtained in live, three-dimensional specimens using quantitative and mechanical approaches. Experiments in which overcrowding was induced in mouse neocortical NE/VZ, as well as comparisons of neocortical INM between mice and ferrets, have revealed that the behavior of NE/VZ cells can be affected by cellular densification. A consideration of the physical aspects in the NE/VZ and the mechanical difficulties associated with high-degree pseudostratification (PS) is important for achieving a better understanding of neocortical development and evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.