Evidence map›Paper›PMID 25674025›Full record

ReviewClinical Medicine Insights. Cardiology2014

Inflammation, Atherosclerosis, and Coronary Artery Disease: PET/CT for the Evaluation of Atherosclerosis and Inflammation.

Nadia Alie, Mootaz Eldib, Zahi A Fayad, Venkatesh Mani

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Clinical Medicine Insights. Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03590769 (Arterial Imaging of Inflammation and Resolution After Endovascular Surgery), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03590769 phase1completednot on this mapstarted 2017, after this paper: background citation

Arterial Imaging of Inflammation and Resolution After Endovascular Surgery

TypeinterventionalSponsorUniversity of California, San FranciscoRan2017 to 2019Enrolled9ConditionsPeripheral Arterial Disease, Claudication, Intermittent, Claudication, PADArms18F-FDG
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 72 citations in OpenAlex.

  1. [EJNMMI research · 2026
    Article
  2. Review
  3. Preclinical evaluation of high-resolution CT,European journal of nuclear medicine and molecular imaging · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Peptide Receptor Radionuclide Therapy UsingDiagnostics (Basel, Switzerland) · 2024
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Mimickers of Large Vessel Giant Cell Arteritis.Journal of clinical medicine · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nadia AlieTranslational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mootaz EldibTranslational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Zahi A FayadTranslational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Venkatesh ManiTranslational and Molecular Imaging Institute, Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Icahn School of Medicine at Mount Sinai · USImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a prevalent cardiovascular disease marked by inflammation and the formation of plaque within arterial walls. As the disease progresses, there is an increased risk of major cardiovascular events. Owing to the nature of atherosclerosis, it is imperative to develop methods to further understand the physiological implications and progression of the disease. The combination of positron emission tomography (PET)/computed tomography (CT) has proven to be promising for the evaluation of atherosclerotic plaques and inflammation within the vessel walls. The utilization of the radiopharmaceutical tracer, 18F-fluorodeoxyglucose ((18)F-FDG), with PET/CT is invaluable in understanding the pathophysiological state involved in atherosclerosis. In this review, we will discuss the use of (18)F-FDG-PET/CT imaging for the evaluation of atherosclerosis and inflammation both in preclinical and clinical studies. The potential of more specific novel tracers will be discussed. Finally, we will touch on the potential benefits of using the newly introduced combined PET/magnetic resonance imaging (MRI) for non-invasive imaging of atherosclerosis.

Indexed as

18F-FDGatherosclerosiscomputed tomographyinflammationplaquepositron emission tomography

Identifiers

PMID25674025
PMCPMC4294600
OpenAlexW2016109210

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.