ArticleJournal of neurophysiology2015
Subcortical functional reorganization due to early blindness.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Sound suppresses earliest visual cortical processing after sight recovery in congenitally blind humans.Communications biology · 2024Article
- The perception of auditory motion in sighted and early blind individuals.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Do you hear what I see? How do early blind individuals experience object motion?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Investigating the neurochemistry of the human visual system using magnetic resonance spectroscopy.Brain structure & function · 2022Review
- Altered Regional Homogeneity in Patients With Congenital Blindness: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in psychiatry · 2022Article
- Role of Structural, Metabolic, and Functional MRI in Monitoring Visual System Impairment and Recovery.Journal of magnetic resonance imaging : JMRI · 2021Review
- Cortical Visual Impairment in Childhood: 'Blindsight' and the Sprague Effect Revisited.Brain sciences · 2021Review
- Human mesenchymal stem cell therapy promotes retinal ganglion cell survival and target reconnection after optic nerve crush in adult rats.Stem cell research & therapy · 2021Article
- The Effect of Congenital and Acquired Bilateral Anophthalmia on Brain Structure.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Neuroplasticity in visual impairments.Neurology international · 2018Article
- Autism Pathogenesis: The Superior Colliculus.Frontiers in neuroscience · 2018Article
- Altered regional homogeneity in patients with late monocular blindness: a resting-state functional MRI study.Neuroreport · 2017Article
- Emotion processing in early blind and sighted individuals.Neuropsychology · 2017Article
- Development of visual category selectivity in ventral visual cortex does not require visual experience.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Using magnetic resonance imaging to assess visual deficits: a review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2016Review
- Adaptive Pulvinar Circuitry Supports Visual Cognition.Trends in cognitive sciences · 2016Review
- Are Supramodality and Cross-Modal Plasticity the Yin and Yang of Brain Development? From Blindness to Rehabilitation.Frontiers in systems neuroscience · 2016Article
- Patterns of Individual Variation in Visual Pathway Structure and Function in the Sighted and Blind.PloS one · 2016Article
- Cortical Plasticity and Olfactory Function in Early Blindness.Frontiers in systems neuroscience · 2016Review
- Neurochemical changes in the pericalcarine cortex in congenital blindness attributable to bilateral anophthalmia.Journal of neurophysiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Lack of visual input early in life results in occipital cortical responses to auditory and tactile stimuli. However, it remains unclear whether cross-modal plasticity also occurs in subcortical pathways. With the use of functional magnetic resonance imaging, auditory responses were compared across individuals with congenital anophthalmia (absence of eyes), those with early onset (in the first few years of life) blindness, and normally sighted individuals. We find that the superior colliculus, a "visual" subcortical structure, is recruited by the auditory system in congenital and early onset blindness. Additionally, auditory subcortical responses to monaural stimuli were altered as a result of blindness. Specifically, responses in the auditory thalamus were equally strong to contralateral and ipsilateral stimulation in both groups of blind subjects, whereas sighted controls showed stronger responses to contralateral stimulation. These findings suggest that early blindness results in substantial reorganization of subcortical auditory responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.