ArticleJournal of neurophysiology2015
Influence of stimulus and oral adaptation temperature on gustatory responses in central taste-sensitive neurons.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Stimulus temperature modulates the psychophysical dimensions of salt taste.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Separation of Oral Cooling and Warming Requires TRPM8.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- TRPV1-Lineage Somatosensory Fibers Communicate with Taste Neurons in the Mouse Parabrachial Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Influences of ethanol and temperature on sucrose-evoked response of gustatory neurons in the hamster solitary nucleus.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021Article
- The neuroscience of sugars in taste, gut-reward, feeding circuits, and obesity.Cellular and molecular life sciences : CMLS · 2020Review
- Interaction of Taste and Place Coding in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Mouse Parabrachial Neurons Signal a Relationship between Bitter Taste and Nociceptive Stimuli.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Modulation of taste processing by temperature.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Review
- Separate functions for responses to oral temperature in thermo-gustatory and trigeminal neurons.Chemical senses · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The temperature of taste stimuli can modulate gustatory processing. Perceptual data indicate that the adapted temperature of oral epithelia also influences gustation, although little is known about the neural basis of this effect. Here, we electrophysiologically recorded orosensory responses (spikes) to 25°C (cool) and 35°C (warm) solutions of sucrose (0.1 and 0.3 M), NaCl (0.004, 0.1, and 0.3 M), and water from taste-sensitive neurons in the nucleus of the solitary tract in mice under varied thermal adaptation of oral epithelia. Conditions included presentation of taste stimuli isothermal to adaptation temperatures of 25°C (constant cooling) and 35°C (constant warming), delivery of 25°C stimuli following 35°C adaptation (relative cooling), and presentation of 35°C stimuli following 25°C adaptation (relative warming). Responses to sucrose in sucrose-oriented cells (n = 15) were enhanced under the constant and relative warming conditions compared with constant cooling, where contiguous cooling across adaptation and stimulus periods induced the lowest and longest latency responses to sucrose. Yet compared with constant warming, cooling sucrose following warm adaptation (relative cooling) only marginally reduced activity to 0.1 M sucrose and did not alter responses to 0.3 M sucrose. Thus, warmth adaptation counteracted the attenuation in sucrose activity associated with stimulus cooling. Analysis of sodium-oriented (n = 25) neurons revealed adaptation to cool water, and cooling taste solutions enhanced unit firing to 0.004 M (perithreshold) NaCl, whereas warmth adaptation and stimulus warming could facilitate activity to 0.3 M NaCl. The concentration dependence of this thermal effect may reflect a dual effect of temperature on the sodium reception mechanism that drives sodium-oriented cells.
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