ArticleProceedings. Biological sciences2015
Biannual birth pulses allow filoviruses to persist in bat populations.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
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Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Influence of Host and Landscape-Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals.Veterinary medicine and science · 2025Pooled it
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- Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology.The Journal of animal ecology · 2026Article
- Assessing Ebola virus circulation in the Tshuapa province (Democratic Republic of the Congo): A One Health investigation of wildlife and human interactions.PLoS pathogens · 2025Article
- Evaluation of long-term immunity following inoculation with highly diverse orthomarburgvirus isolates in Egyptian rousette bats (Journal of virology · 2025Article
- Disease resistance is more costly at younger ages: An explanation for the maintenance of juvenile susceptibility in a wild plant.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Bat Viral Shedding: A Review of Seasonal Patterns and Risk Factors.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2025Review
- High astrovirus diversity in an endemic bat species suggests multiple spillovers from synanthropic rodents and birds.Journal of virology · 2025Article
- Stochastic analysis of Ebola infection in small zoonotic niches.Royal Society open science · 2024Article
- Article
- Modelling Lassa virus dynamics in West AfricanJournal of the Royal Society, Interface · 2024Article
- Metagenomic Sequencing of Lloviu Virus from Dead Schreiber's Bats in Bosnia and Herzegovina.Microorganisms · 2023Article
- Robust evidence for bats as reservoir hosts is lacking in most African virus studies: a review and call to optimize sampling and conserve bats.Biology letters · 2023Review
- Article
- Bartonella infections are prevalent in rodents despite efficient immune responses.Parasites & vectors · 2023Article
- Transmission dynamics of lyssavirus inProceedings. Biological sciences · 2023Article
- Synchronicity of viral shedding in molossid bat maternity colonies.Epidemiology and infection · 2023Article
- Reproduction, seasonal morphology, and juvenile growth in three Malagasy fruit bats.Journal of mammalogy · 2022Article
- Can disease resistance evolve independently at different ages? Genetic variation in age-dependent resistance to disease in three wild plant species.The Journal of ecology · 2022Article
- Isolation of infectious Lloviu virus from Schreiber's bats in Hungary.Nature communications · 2022Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Filoviruses Ebolavirus (EBOV) and Marburgvirus (MARV) cause haemorrhagic fevers with high mortality rates, posing significant threats to public health. To understand transmission into human populations, filovirus dynamics within reservoir host populations must be understood. Studies have directly linked filoviruses to bats, but the mechanisms allowing viral persistence within bat populations are poorly understood. Theory suggests seasonal birthing may decrease the probability of pathogen persistence within populations, but data suggest MARV may persist within colonies of seasonally breeding Egyptian fruit bats, Rousettus aegyptiacus. I synthesize available filovirus and bat data in a stochastic compartmental model to explore fundamental questions relating to filovirus ecology: can filoviruses persist within isolated bat colonies; do critical community sizes exist; and how do host-pathogen relationships affect spillover transmission potential? Synchronous annual breeding and shorter incubation periods did not allow filovirus persistence, whereas bi-annual breeding and longer incubation periods, such as reported for Egyptian fruit bats and EBOV in experimental studies, allowed persistence in colony sizes often found in nature. Serological data support the findings, with bats from species with two annual birth pulses more likely to be seropositive (odds ratio (OR) 4.4, 95% confidence interval (CI) 2.5-8.7) than those with one, suggesting that biannual birthing is necessary for filovirus persistence.
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