ArticleClinical trials (London, England)2015
Clinical trial awareness: Changes over time and sociodemographic disparities.
Article in Clinical trials (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Trial Generalizability Assessment in the Big Data Era: A Review.Clinical and translational science · 2020Pooled it
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- Mapping the path to diversity in clinical trials: a qualitative study of community member and stakeholder perspectives.BMC public health · 2025Article
- Experiences of Racism in Health Care and Medical Mistrust Shape Cancer Prevention and Control Behaviors Among Black Residents of Black Hawk County, Iowa: A Qualitative Study.Journal of racial and ethnic health disparities · 2025Article
- CLEAR: A vision to support clinical evidence lifecycle with continuous learning.Journal of biomedical informatics · 2025Article
- Effect of HLA restriction on racial and ethnic disparities in access to immune therapies for advanced synovial sarcoma.The oncologist · 2025Article
- Attitude of patients with liver cancer toward clinical drug trials: empirical qualitative research.Scientific reports · 2025Article
- Beyond Barriers: Achieving True Equity in Cancer Care.Current oncology (Toronto, Ont.) · 2025Review
- Disparities in Clinical Trial Participation in Children and Adolescent Patients With a Hematologic Malignancy.Pediatric blood & cancer · 2025Article
- Clinical trial knowledge, discussion, and participation among cancer survivors: A HINTS-SEER study.Patient education and counseling · 2025Article
- Disparities in cancer clinical trials information-seeking: Findings from the National Cancer Institute's Cancer Information Service.Patient education and counseling · 2024Article
- Knowledge and Beliefs about Clinical Trials among Adults in Poland: A Cross-Sectional Study.Clinics and practice · 2024Article
- Racial Disparities in Clinical Trial Enrollment Among Patients Diagnosed With Prostate Cancer: A Population-Based Cohort of Oncology Practices.Advances in urology · 2024Article
- Recommending Clinical Trials for Online Patient Cases using Artificial Intelligence.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
- The influence of political ideology on clinical trial knowledge, invitation, and participation among adults in the United States.Clinical trials (London, England) · 2023Article
- Selection and Prejudice: Addressing Clinical Trial Disparities With a Review of Current Shortcomings and Future Directions.Seminars in radiation oncology · 2023Review
- Geographic and socioeconomic access disparities to Phase 3 clinical trials in ophthalmology in the United States.Eye (London, England) · 2023Article
- Article
- Factors affecting the recruitment of Hispanic/Latinx American older adults in clinical trials in the United States: A scoping review.Journal of the American Geriatrics Society · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND OR
aimsLack of clinical trial awareness is a known obstacle to clinical trial enrollment. We sought to define the prevalence of clinical trial awareness in the US population, determine characteristics associated with increased trial awareness, and explore potential disparities in trial awareness.
methodsWe utilized data from the Health Information National Trends Survey from 2008 and 2012. Logistic regression was utilized to assess predictors of clinical trial awareness, particularly sociodemographic variables and information-seeking preferences. Trial awareness and information-seeking preferences were compared in patient subgroups and between the two time periods.
resultsClinical trial awareness increased from 68% to 74% between 2008 and 2012. In the 2012 dataset, higher education level (odds ratio: 3.52, 95% confidence interval: 2.16-5.74), higher yearly income category (odds ratio: 1.84, 95% confidence interval: 1.17-2.89), and Internet use (odds ratio: 2.13, 95% confidence interval: 1.52-3.00) were significantly associated with clinical trial awareness. Hispanic ethnicity (odds ratio: 0.41, 95% confidence interval: 0.25-0.68) was significantly associated with decreased awareness. Clinical trial awareness increased in African-American/Blacks (Δ10.6%) and Hispanics (Δ10.7%) between 2008 and 2012, as did Internet use in both subgroups (Δ14.2%, Δ18.1%, respectively).
conclusionOverall clinical trial awareness has increased between 2008 and 2012, although a large subset of the population still lacks general awareness of clinical trials. Racial and ethnic disparities in trial awareness exist, although disparities may be decreasing among the Black population. These findings may help target educational efforts and inform approaches to increasing trial awareness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.