Observational studyInternational urology and nephrology2015
Depressive symptoms in patients diagnosed with benign prostatic hyperplasia.
Observational study in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07552961 (Evaluating the Feasibility of a Comprehensive Prehabilitation Program for Use in Benign Prostatic Hyperplasia Patients Undergoing Holmium Laser Enucleation of the Prostate), which is not on this map. Cited by 18 papers.
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Evaluating the Feasibility of a Comprehensive Prehabilitation Program for Use in Benign Prostatic Hyperplasia Patients Undergoing Holmium Laser Enucleation of the Prostate
Who cites it
18 citing papers in PubMed.
- Risk of New-Onset Postoperative Depression After Holmium Laser Enucleation Versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: A Nationwide Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Impact of Fixed-Dose Combination Versus Single-Component Therapy for Benign Prostatic Hyperplasia-Related Urinary Symptoms on Persistence, Adherence, and Satisfaction in a Real-Life Setting.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Article
- Factors associated with depressive symptoms in patients with benign prostatic enlargement.African journal of primary health care & family medicine · 2023Article
- Effects of major depression and bipolar disorder on erectile dysfunction: a two-sample mendelian randomization study.BMC medical genomics · 2023Article
- Exploring potential genes and mechanisms linking erectile dysfunction and depression.Frontiers in endocrinology · 2023Article
- Serum prostate specific antigen is a good indicator of prostatic volume in men with benign prostatic hyperplasia.African journal of primary health care & family medicine · 2022Article
- Association of 5α-Reductase Inhibitors With Dementia, Depression, and Suicide.JAMA network open · 2022Article
- Association between benign prostatic hyperplasia and suicide in South Korea: A nationwide retrospective cohort study.PloS one · 2022Article
- Efficacy of a combination of dutasteride, tadalafil, and solifenacin in the treatment of previously unsuccessful patients.Asian journal of urology · 2022Article
- The Circadian Syndrome Predicts Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia Better Than Metabolic Syndrome in Aging Males: A 4-Year Follow-Up Study.Frontiers in medicine · 2021Article
- Risk of Depression after 5 Alpha Reductase Inhibitor Medication: Meta-Analysis.The world journal of men's health · 2020Article
- BPH: Why Do Patients Fail Medical Therapy?Current urology reports · 2019Review
- Long-term Consequences of Medical Therapy for Benign Prostatic Hyperplasia.Reviews in urology · 2019Article
- The Correlation between Body Mass Index and Routine Parameters in Men Over Fifty.The world journal of men's health · 2017Article
- Association of Suicidality and Depression With 5α-Reductase Inhibitors.JAMA internal medicine · 2017Article
- Men With Severe Lower Urinary Tract Symptoms Are at Increased Risk of Depression.International neurourology journal · 2015Article
- Evaluation of intermittent tamsulosin in treating symptomatic patients with benign prostatic hyperplasia.Urology annalsArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptoms of depression are common in patients diagnosed with benign prostatic hyperplasia (BPH) and are usually a reaction to deterioration of health, severity of lower urinary tract symptoms, and erectile dysfunction. The aim of this observational study was to evaluate the prevalence of depressive symptoms in patients diagnosed with BPH and factors affecting their occurrence in a large Polish cohort. PATIENTS AND
methodsFour thousand thirty-five men (4,035) diagnosed with BPH participated in the survey (age 65 ± 8 years). The occurrence of symptoms of depression was assessed using the Beck depression inventory, severity of lower urinary tract symptoms (LUTS) on the basis of the international prostate symptoms score, and erectile dysfunction using the international index of erectile function (IIEF-5).
resultsDepressive symptoms were found in 22.4% of patients (mild in 20.8% and moderate/severe in 1.6%). Erectile dysfunction was found in 71.9% of patients. Monotherapy for BPH was prescribed to 50.9% of patients (mostly ARA-selective α1-selective alpha-adrenolytic-47.5%), while polytherapy (ARA with a 5-alpha reductase inhibitor-5αRI) to 47.9%. Logistic regression analysis showed a bidirectional relation between the occurrence of depressive symptoms and erectile dysfunction. The occurrence of both depressive symptoms and erectile dysfunction was related to severity of LUTS, nocturia, the use of 5αRI, comorbidity, and sedentary life style.
conclusionsPrevalence of depressive symptoms in patients diagnosed with BPH is associated with severity of LUTS, erectile dysfunction, nocturia, BPH pharmacotherapy (5αRIs), sedentary life style, and comorbidities including obesity.
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