Evidence map›Paper›PMID 25672839›Full record

ArticleCritical care (London, England)2014

TEG®- or ROTEM®-based individualized goal-directed coagulation algorithms: don't wait--act now!

Donat R Spahn

Abstract readComment
In one paragraph

Article in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Terrorist incidents: strategic treatment objectives, tactical diagnostic procedures and the estimated need of blood and clotting products.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Measuring fibrinolysis: from research to routine diagnostic assays.Journal of thrombosis and haemostasis : JTH · 2018
    Review
  12. The impact of early thromboelastography directed therapy in trauma resuscitation.Scandinavian journal of trauma, resuscitation and emergency medicine · 2017
    Article
  13. Is viscoelastic coagulation monitoring with ROTEM or TEG validated?Scandinavian journal of clinical and laboratory investigation · 2016
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Donat R Spahn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In trauma patients, TEG® and ROTEM® allow prediction of massive transfusion requirement and mortality, and creation of goal-directed, individualized coagulation algorithms that may improve patient outcome. This outcome benefit has been shown for cardiac surgery in prospective randomized trials. For trauma, only non-randomized studies have been performed. Nevertheless, TEG® and ROTEM® are highly promising monitoring techniques to guide coagulation management in all types of major bleeding, including trauma.

Indexed as

Blood TransfusionBlood Coagulation DisordersHumansThrombelastographyWounds and Injuries

Identifiers

PMID25672839
PMCPMC4331375

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.