Evidence map›Paper›PMID 25672596›Full record

ArticleJournal of materials science. Materials in medicine2015

Characterization of gelatin-agar based phase separated hydrogel, emulgel and bigel: a comparative study.

Senggam Wakhet, Vinay K Singh, Saikat Sahoo, Sai Sateesh Sagiri, Senthilguru Kulanthaivel, Mrinal K Bhattacharya, Naresh Kumar, Indranil Banerjee, Kunal Pal

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Senggam WakhetDepartment of Biotechnology & Medical Engineering, National Institute of Technology, Rourkela, 769008, Odisha, India.
Vinay K Singh
Saikat Sahoo
Sai Sateesh Sagiri
Senthilguru Kulanthaivel
Mrinal K Bhattacharya
Naresh Kumar
Indranil Banerjee
Kunal Pal

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study describes the in-depth characterization of agar-gelatin based co-hydrogels, emulgels and bigels to have an insight about the differences in the properties of the formulations. Hydrogels have been extensively studied as vehicle for controlled drug release, whereas, the concept of emulgels and bigels is relatively new. The formulations were characterized by scanning electron microscopy, FTIR spectroscopy, XRD and mechanical properties. The biocompatibility and the ability of the formulations to be used as drug delivery vehicle were also studied. The scanning electron micrographs suggested the presence of internal phases within the agar-gelatin composite matrices of co-hydrogel, emulgel and bigel. FTIR and XRD studies suggested higher crystallinity of emulgels and bigels. Electrical impedance and mechanical stability of the emulgel and the bigel was higher than the hydrogel. The prepared formulations were found to be biocompatible and suitable for drug delivery applications.

Indexed as

AgarAnti-Infective AgentsCompressive StrengthDelayed-Action PreparationsDiffusionElastic ModulusGelatinHardnessHydrogelsMaterials TestingMetronidazolePhase TransitionAgarAnti-Infective AgentsDelayed-Action PreparationsGelatinHydrogelsMetronidazole

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.