ArticleEpidemiology and infection2015
High prevalence of hepatitis C (HCV) in the emergency department (ED) of a London hospital: should we be screening for HCV in ED attendees?
Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Community Versus Facility-Based Services to Improve the Screening of Active Hepatitis C Virus Infection in Cambodia: The ANRS 12384 CAM-C Cluster Randomized Controlled Trial-Protocol for a Mixed Methods Study.JMIR research protocols · 2024Article
- Elimination of hepatitis C in a hospital characterized by infectious diseases.Frontiers in public health · 2023Article
- Real-world clinical effectiveness and sustainability of universal bloodborne virus testing in an urban emergency department in the UK.Scientific reports · 2022Article
- High Rates of Hidden HCV Infections among Hospitalized Patients Aged 55-85.Pathogens (Basel, Switzerland) · 2021Article
- [In-hospital process for viral hepatitis C screening and management in China (Draft)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021Article
- Non-Invasive Reliable Methods to Objectify the Positive Influence of Hepatitis C Virus Treatment on Liver Stiffness.Gastroenterology research · 2021Article
- [Establishment and implementation of hepatitis C screening and referral channels in the hospitals].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020Article
- Emergency department targeted screening for hepatitis C does not improve linkage to care.World journal of gastroenterology · 2020Article
- Hepatitis B screening in an argentine ED: Increasing vaccination in a resource-limited setting.The American journal of emergency medicine · 2020Article
- Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department.Canadian journal of gastroenterology & hepatology · 2020Observational
- Consistent high prevalence of undiagnosed blood-borne virus infection in patients attending large urban emergency departments in England.Journal of viral hepatitis · 2020Article
- Seroprevalence and demographic factors associated with hepatitis B, hepatitis C and HIV infection from a hospital emergency department testing programme, London, United Kingdom, 2015 to 2016.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- Low hepatitis C prevalence in Belgium: implications for treatment reimbursement and scale up.BMC public health · 2019Article
- Retrospective hepatitis C seroprevalence screening in the antenatal setting-should we be screening antenatal women?BMJ open · 2016Article
- Evaluation of a strategy for identification of hepatitis C virus carriers in outpatient and emergency units: contribution to the microelimination of hepatitis C in Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An unlinked anonymous study was conducted to estimate the prevalence of hepatitis C virus (HCV) infection in emergency department (ED) attendees at a London Hospital. Nine hundred and ninety-seven samples collected over a 12-day period were tested for HCV antibody (Ab) and reactive samples were further tested for HCV RNA. The HCV seroprevalence was 2·6% (26/997) with 1·2% (12/997) HCV RNA positive. A peak HCV RNA-positive prevalence of 4·8% (3/63) was found in males aged 35-44 years, this was compared to 0% (0/136) in males aged <35 years (P = 0·0614) and 1·4% (4/278) in males aged ⩾45 years (P = 0·2415). Assuming the cost for HCV Ab is £6 and HCV RNA is £40 per test, screening ED attendees aged 25-54 years would cost £360 per viraemic infection and identify 82% of those who were HCV RNA positive, yielding the most favourable cost/benefit ratio. HCV screening of ED attendees aged 25-54 years in this population could be an effective way of identifying patients and limit onward transmission.
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Registered trials
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