Evidence map›Paper›PMID 25672399›Full record

ArticleEpidemiology and infection2015

Use of random forest to estimate population attributable fractions from a case-control study of Salmonella enterica serotype Enteritidis infections.

W Gu, A R Vieira, R M Hoekstra, P M Griffin, D Cole

Abstract read
In one paragraph

Article in Epidemiology and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  6. Prediction ofLife (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

W GuCenters for Disease Control and Prevention, Enteric Diseases Epidemiology Branch,Atlanta,GA,USA.
A R VieiraCenters for Disease Control and Prevention, Enteric Diseases Epidemiology Branch,Atlanta,GA,USA.
R M HoekstraCenters for Disease Control,Division of Foodborne,Waterborne and Environmental Diseases Atlanta,GA,USA.
P M GriffinCenters for Disease Control and Prevention, Enteric Diseases Epidemiology Branch,Atlanta,GA,USA.
D ColeCenters for Disease Control and Prevention, Enteric Diseases Epidemiology Branch,Atlanta,GA,USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To design effective food safety programmes we need to estimate how many sporadic foodborne illnesses are caused by specific food sources based on case-control studies. Logistic regression has substantive limitations for analysing structured questionnaire data with numerous exposures and missing values. We adapted random forest to analyse data of a case-control study of Salmonella enterica serotype Enteritidis illness for source attribution. For estimation of summary population attributable fractions (PAFs) of exposures grouped into transmission routes, we devised a counterfactual estimator to predict reductions in illness associated with removing grouped exposures. For the purpose of comparison, we fitted the data using logistic regression models with stepwise forward and backward variable selection. Our results show that the forward and backward variable selection of logistic regression models were not consistent for parameter estimation, with different significant exposures identified. By contrast, the random forest model produced estimated PAFs of grouped exposures consistent in rank order with results obtained from outbreak data, with egg-related exposures having the highest estimated PAF (22·1%, 95% confidence interval 8·5-31·8). Random forest might be structurally more coherent and efficient than logistic regression models for attributing Salmonella illnesses to sources involving many causal pathways.

Indexed as

Decision TreesAnimalsCase-Control StudiesDisease OutbreaksFood MicrobiologyHumansLogistic ModelsPredictive Value of TestsRisk FactorsSalmonella enteritidisSalmonella Food PoisoningSerogroupUnited StatesCausalitycounterfactualfoodborne diseaseslogistic regressionmachine learning

Identifiers

PMID25672399
PMCPMC9151037

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.