Evidence map›Paper›PMID 25672277›Full record

ArticleIntensive care medicine2015

ICU survivors show no decline in health-related quality of life after 5 years.

José G M Hofhuis, Henk F van Stel, Augustinus J P Schrijvers, Johannes H Rommes, Peter E Spronk

Abstract read
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In one paragraph

Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Long-term Survival after Critical Illness: Are We There Yet?Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  8. Article
  9. Article
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  13. What matters most to sepsis survivors: a qualitative analysis to identify specific health-related quality of life domains.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. [Intensive care medicine-survival and prospect of life].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017
    Review
  19. Article
  20. Fatigue in intensive care survivors one year after discharge.Health and quality of life outcomes · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José G M HofhuisDepartment of Intensive Care, Gelre Ziekenhuizen Hospital, Albert Schweitzerlaan 31, 7334 DZ, Apeldoorn, The Netherlands, j.hofhuis@gelre.nl.
Henk F van Stel
Augustinus J P Schrijvers
Johannes H Rommes
Peter E Spronk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSevere critical illness requiring treatment in the intensive care unit (ICU) may have a serious impact on patients and their families. However, optimal follow-up periods are not defined and data on health-related quality of life (HRQOL) before ICU admission as well as those beyond 2 years follow-up are limited. The aim of our study was to assess the impact of ICU stay up to 5 years after ICU discharge.

methodsWe performed a long-term prospective cohort study in patients admitted for longer than 48 h in a medical-surgical ICU. The Short-Form 36 was used to evaluate HRQOL before admission (by proxy within 48 h after admission of the patient), at ICU discharge, and at 1, 2, and 5 years following ICU discharge (all by patients). Changes in HRQOL were assessed using linear mixed modeling.

resultsWe included a total of 749 patients (from 2000 to 2007). At 5 years after ICU discharge 234 patients could be evaluated. After correction for natural decline in HRQOL, the mean scores of four dimensions-physical functioning (p < 0.001), role-physical (p < 0.001), general health (p < 0.001), and social functioning (p = 0.003)-were still significantly lower 5 years after ICU discharge compared with their pre-admission levels, although effect sizes were small (<0.5).

conclusionsAfter correction for natural decline, the effect sizes of decreases in HRQOL were small, suggesting that patients regain their age-specific HRQOL 5 years after their ICU stay.

Indexed as

Critical CareCritical IllnessQuality of LifeSurvivorsAgedFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle AgedProspective Studies

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.