ReviewRestorative dentistry & endodontics2015
Epigenetics: general characteristics and implications for oral health.
Review in Restorative dentistry & endodontics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Holobiontic Intercellular Relationships Between the Oral Cavity and the Rest of the Human Organism: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- DNA Methylation of COX-2, IFN-γ, TNF-α, and LINE-1 in Clinically Stable Periodontal Tissues Following Periodontal Therapy.Clinical and experimental dental research · 2025Article
- Conversation between skin microbiota and the host: from early life to adulthood.Experimental & molecular medicine · 2025Review
- Effect of Long Non-coding RNA and DNA Methylation on Gene Expression in Dental Fluorosis.Biological trace element research · 2024Article
- The Potential Role of Epigenetic Modifications on Different Facets in the Periodontal Pathogenesis.Genes · 2023Review
- Role of epigenetics in OSCC: an understanding above genetics.Medical oncology (Northwood, London, England) · 2023Review
- Downregulation of miRNA-26 in chronic periodontitis interferes with innate immune responses and cell migration by targeting phospholipase C beta 1.Journal of clinical periodontology · 2023Article
- Stabilizing and Anti-Repressor Elements Effectively Increases Transgene Expression in Transfected CHO Cells.Frontiers in bioengineering and biotechnology · 2022Article
- Your health is in your mouth: A comprehensive view to promote general wellness.Frontiers in oral health · 2022Review
- Basics of Epigenetics and Role of Epigenetics in Diabetic Complications.Journal of pharmacy & bioallied sciences · 2021Article
- Photobiomodulation therapy improves human dental pulp stem cell viability and migration in vitro associated to upregulation of histone acetylation.Lasers in medical science · 2020Article
- One-Carbon Metabolism Links Nutrition Intake to Embryonic Development via Epigenetic Mechanisms.Stem cells international · 2019Review
- Current Concepts of Epigenetics and Its Role in Periodontitis.Current oral health reports · 2017Review
- Epigenetic regulation in dental pulp inflammation.Oral diseases · 2017Review
- Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells.The Yale journal of biology and medicine · 2016Review
- Epigenetics and Periodontitis: A Contemporary Review.Journal of clinical and diagnostic research : JCDR · 2016Review
- Protocol for assessing maternal, environmental and epigenetic risk factors for dental caries in children.BMC oral health · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic information such as DNA sequences has been limited to fully explain mechanisms of gene regulation and disease process. Epigenetic mechanisms, which include DNA methylation, histone modification and non-coding RNAs, can regulate gene expression and affect progression of disease. Although studies focused on epigenetics are being actively investigated in the field of medicine and biology, epigenetics in dental research is at the early stages. However, studies on epigenetics in dentistry deserve attention because epigenetic mechanisms play important roles in gene expression during tooth development and may affect oral diseases. In addition, understanding of epigenetic alteration is important for developing new therapeutic methods. This review article aims to outline the general features of epigenetic mechanisms and describe its future implications in the field of dentistry.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.