ReviewBioImpacts : BI2014
Nanoscaled aptasensors for multi-analyte sensing.
Review in BioImpacts : BI, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Trends and Challenges of SPR Aptasensors in Viral Diagnostics: A Systematic Review and Meta-Analysis.Biosensors · 2025Pooled it
- Electrochemical Nanostructured Aptasensor for Direct Detection of Glycated Hemoglobin.International journal of molecular sciences · 2025Article
- Electrochemical Biosensors for the Detection of Antibiotics in Milk: Recent Trends and Future Perspectives.Biosensors · 2023Review
- Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers.BioImpacts : BI · 2023Article
- Label-free electrochemical microfluidic biosensors: futuristic point-of-care analytical devices for monitoring diseases.Mikrochimica acta · 2022Review
- Microfluidic paper-based analytical devices (µPADs) for fast and ultrasensitive sensing of biomarkers and monitoring of diseases.BioImpacts : BI · 2018Article
- Nucleic acid aptamer application in diagnosis and therapy of colorectal cancer based on cell-SELEX technology.NPJ precision oncology · 2017Review
- High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency.Scientific reports · 2016Article
- Computerized techniques pave the way for drug-drug interaction prediction and interpretation.BioImpacts : BI · 2016Review
- A Highlight of Recent Advances in Aptamer Technology and Its Application.Molecules (Basel, Switzerland) · 2015Review
- Aptamer Technology and Its Applications in Bone Diseases.Cell transplantationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNanoscaled aptamers (Aps), as short single-stranded DNA or RNA oligonucleotides, are able to bind to their specific targets with high affinity, upon which they are considered as powerful diagnostic and analytical sensing tools (the so-called "aptasensors"). Aptamers are selected from a random pool of oligonucleotides through a procedure known as "systematic evolution of ligands by exponential enrichment".
methodsIn this work, the most recent studies in the field of aptasensors are reviewed and discussed with a main focus on the potential of aptasensors for the multianalyte detection(s).
resultsDue to the specific folding capability of aptamers in the presence of analyte, aptasensors have substantially successfully been exploited for the detection of a wide range of small and large molecules (e.g., drugs and their metabolites, toxins, and associated biomarkers in various diseases) at very low concentrations in the biological fluids/samples even in presence of interfering species.
conclusionBiological samples are generally considered as complexes in the real biological media. Hence, the development of aptasensors with capability to determine various targets simultaneously within a biological matrix seems to be our main challenge. To this end, integration of various key scientific dominions such as bioengineering and systems biology with biomedical researches are inevitable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.