Tailoring the ligand shell for the control of cellular uptake and optical properties of nanocrystals.

Johannes Ostermann, Christian Schmidtke, Christopher Wolter, Jan-Philip Merkl, Hauke Kloust, Horst Weller

Abstract readReview

In one paragraph

Review in Beilstein journal of nanotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Synthesis of Polystyrene-Coated Superparamagnetic and Ferromagnetic Cobalt Nanoparticles.Polymers · 2018
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johannes OstermannInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Christian SchmidtkeInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Christopher WolterInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Jan-Philip MerklInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Hauke KloustInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany.

Horst WellerInstitute for Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg, Germany ; Center for Applied Nanotechnology, Grindelallee 117, 20146 Hamburg, Germany ; The Hamburg Centre for Ultrafast Imaging, University of Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany ; Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this short review, the main challenges in the use of hydrophobic nanoparticles in biomedical application are addressed. It is shown how to overcome the different issues by the use of a polymeric encapsulation system, based on an amphiphilic polyisoprene-block-poly(ethylene glycol) diblock copolymer. On the basis of this simple molecule, the development of a versatile and powerful phase transfer strategy is summarized, focusing on the main advantages like the adjustable size, the retained properties, the excellent shielding and the diverse functionalization properties of the encapsulated nanoparticles. Finally, the extraordinary properties of these encapsulated nanoparticles in terms of toxicity and specificity in a broad in vitro test is demonstrated.

Indexed as

biolablecellular uptakefluorescence quenchingpoylmeric micellesquantum dots

Identifiers

PMID25671167

DOI10.3762/bjnano.6.22

PMCPMC4311591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.