Evidence map›Paper›PMID 25669880›Full record

ArticleDevelopmental cell2015

Toward a new twist in Hox and TALE DNA-binding specificity.

Samir Merabet, Ingrid Lohmann

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Samir MerabetInstitut de Génomique Fonctionnelle de Lyon (IGFL), UMR5242, ENS Lyon, 46 Allée d'Italie, 69007 Lyon, France. Electronic address: samir.merabet@ens-lyon.fr.
Ingrid LohmannDepartment of Developmental Biology, Centre for Organismal Studies, University of Heidelberg, Im Neuenheimer Feld 230, D-69120 Heidelberg, Germany. Electronic address: ingrid.lohmann@bioquant.uni-heidelberg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hox proteins gain specificity by interacting with TALE-class cofactors. In a recent issue of Cell and in this issue of Developmental Cell, Crocker et al. (2015) and Amin et al. (2015), respectively, demonstrate that non-canonical Hox/TALE binding sequences play a major role in the regionalized regulation of target gene expression in vivo.

Indexed as

Enhancer Elements, GeneticAnimalsBranchial RegionDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalHomeodomain ProteinsTranscription FactorsDNA-Binding ProteinsDrosophila ProteinsHomeodomain ProteinsHoxa2 protein, mouseTranscription Factors

Identifiers

PMID25669880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.