ArticleSleep2015
Preterm Infants Exhibit Greater Variability in Cerebrovascular Control than Term Infants.
Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Practical Application of Polysomnography in Infants.Journal of clinical medicine · 2025Review
- Near-infrared spectroscopy monitoring of neonatal cerebrovascular reactivity: where are we now?Pediatric research · 2024Review
- Cerebrovascular responses to a 90° tilt in healthy neonates.Pediatric research · 2024Article
- Sympathetic nervous system activity and pain-related response indexed by electrodermal activity during the earliest postnatal life in healthy term neonates.Physiological research · 2023Article
- Stabilizing breathing pattern using local mechanical vibrations: comparison of deterministic and stochastic stimulations in rodent models of apnea of prematurity.Biomedical engineering letters · 2021Article
- Effects of tilt on cerebral hemodynamics measured by NeoDoppler in healthy neonates.Pediatric research · 2021Article
- Article
- Regional tissue oxygenation monitoring in the neonatal intensive care unit: evidence for clinical strategies and future directions.Pediatric research · 2019Review
- Neonatal circumcision and prematurity are associated with sudden infant death syndrome (SIDS).Journal of clinical and translational research · 2019Article
- Autonomic nervous system development and its impact on neuropsychiatric outcome.Pediatric research · 2019Review
- The Critical Role of the Central Autonomic Nervous System in Fetal-Neonatal Transition.Seminars in pediatric neurology · 2018Review
- Waking up too early - the consequences of preterm birth on sleep development.The Journal of physiology · 2018Review
- Cardiovascular autonomic dysfunction in sudden infant death syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018Review
- Autonomic nervous system depression at term in neurologically normal premature infants.Early human development · 2018Article
- Endothelial Colony-Forming Cells in Young Adults Born Preterm: A Novel Link Between Neonatal Complications and Adult Risks for Cardiovascular Disease.Journal of the American Heart Association · 2018Observational
- A "Wear and Tear" Hypothesis to Explain Sudden Infant Death Syndrome.Frontiers in neurology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesSudden infant death syndrome (SIDS) remains an important cause of infant death, particularly among infants born preterm. Prone sleeping is the major risk factor for SIDS and this has recently been shown to alter cerebrovascular control in term infants. As preterm infants are at greater risk for SIDS than those born at term, we hypothesized that their cerebrovascular control in the prone position would be reduced compared to term infants. PATIENTS OR
participantsThere were 35 preterm (mean gestation 31.2 ± 0.4 w) and 17 term (mean gestation 40.1 ± 0.3 w) infants.
designInfants underwent daytime polysomnography at 2-4 w, 2-3 mo, and 5-6 mo postterm age. Infants slept both prone and supine and were presented with cardiovascular challenges in the form of 15° head-up tilts (HUT). MEASUREMENTS AND
resultsCerebral tissue oxygenation index (TOI) was recorded using near-infrared spectroscopy (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and mean arterial pressure (MAP) was recorded using a Finometer cuff (Finapres Medical Systems, Amsterdam, The Netherlands). In the prone position TOI increased following the HUT (P < 0.05), whereas no change was seen in the supine position. The overall pattern of response was similar in both groups, but more variable in preterm than term infants (P < 0.05).
conclusionsCerebrovascular control differs between the prone and supine positions in preterm infants. Although overall the responses to head-up tilts were similar between term and preterm infants, greater variability of responses in preterm infants suggests persisting immaturity of their cerebrovascular control in the first year of life, which may contribute to their increased risk of sudden infant death syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.