Trial reportSleep2015
Local increase of sleep slow wave activity after three weeks of working memory training in children and adolescents.
Trial report in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- The infraslow fluctuation of sigma power during sleep and its links to markers of arousal and memory reactivation across development.Scientific reports · 2026Article
- Mapping the Digital Mind: A Meta-Analysis of EEG Biomarkers in Cognition, Emotion, and Mental Health.Brain sciences · 2026Review
- Effect of a Power Mobility Intervention on the Sleep Health of Toddlers with Cerebral Palsy.Physical & occupational therapy in pediatrics · 2026Article
- The Space-Time Organisation of Sleep Slow Oscillations as Potential Biomarker for Hypersomnolence.Journal of sleep research · 2025Article
- The Infraslow Fluctuation of Sigma Power During Sleep in Young Individuals with Schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Efficient Sleep, Enhanced Attention: Exploring the Interplay With RBC-Inflammation Mechanisms in Hypoxic High-Altitude Areas.Nature and science of sleep · 2025Article
- Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain.PLoS computational biology · 2024Article
- Emergent effects of synaptic connectivity on the dynamics of global and local slow waves in a large-scale thalamocortical network model of the human brain.bioRxiv : the preprint server for biology · 2024Article
- Positive or negative environmental modulations on human brain development: the morpho-functional outcomes of music training or stress.Frontiers in neuroscience · 2023Review
- Understanding the roles of central and autonomic activity during sleep in the improvement of working memory and episodic memory.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Extreme conditions affect neuronal oscillations of cerebral cortices in humans in the China Space Station and on Earth.Communications biology · 2022Article
- Effects of Multisession Prefrontal Transcranial Direct Current Stimulation on Long-term Memory and Working Memory in Older Adults.Journal of cognitive neuroscience · 2022Article
- Competitive dynamics underlie cognitive improvements during sleep.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Post-training stimulation of the right dorsolateral prefrontal cortex impairs working memory training performance.Journal of neuroscience research · 2021Article
- Homeostasis Research Model Based on Yin-Yang Theory: Five Examples.Chinese journal of integrative medicine · 2021Review
- Sleep in 21-Day Dry Immersion. Are Cardiovascular Adjustments Rapid Eye Movement Sleep-Dependent?Frontiers in physiology · 2021Article
- Neural correlates of memory recovery: Preliminary findings in children and adolescents with acquired brain injury.Restorative neurology and neuroscience · 2021Article
- Sleep EEG slow-wave activity in medicated and unmedicated children and adolescents with attention-deficit/hyperactivity disorder.Translational psychiatry · 2019Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesEvidence is accumulating that electroencephalographic (EEG) sleep slow wave activity (SWA), the key characteristic of deep sleep, is regulated not only globally, but also locally. Several studies have shown local learning- and use-dependent changes in SWA. In vitro and in vivo animal experiments and studies in humans indicate that these local changes in SWA reflect synaptic plasticity. During maturation, when synaptic changes are most prominent, learning is of utmost importance. Thus, in this study, we aimed to examine whether intensive working memory training for 3 w would lead to a local increase of sleep SWA using high-density EEG recordings in children and young adolescents.
settingSleep laboratory at the University Children's Hospital Zurich.
participantsFourteen healthy subjects between 10 and 16 y.
interventionsThree weeks of intensive working memory training. MEASUREMENTS AND
resultsAfter intensive working memory training, sleep SWA was increased in a small left frontoparietal cluster (11.06 ± 1.24%, mean ± standard error of the mean). In addition, the local increase correlated positively with increased working memory performance assessed immediately (r = 0.66) and 2 to 5 mo (r = 0.68) after the training.
conclusionsThe increase in slow wave activity (SWA) correlates with cognitive training-induced plasticity in a region known to be involved in working memory performance. Thus, in future, the mapping of sleep SWA may be used to longitudinally monitor the effects of working memory training in children and adolescents with working memory deficiencies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.