ArticleSleep2015
25-Hydroxyvitamin D Concentration and Sleep Duration and Continuity: Multi-Ethnic Study of Atherosclerosis.
Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants.Atherosclerosis · 2026Pooled it
- The relationship between micronutrient status and sleep patterns: a systematic review.Public health nutrition · 2017Pooled it
- Repletion of vitamin D associated with deterioration of sleep quality among postmenopausal women.Preventive medicine · 2016Trial
- Association of vitamin D and B12 levels with actigraphic sleep in cognitively unimpaired middle-aged and older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Joint association of weekend catch-up sleep and triglyceride-glucose index on bone loss and all-cause mortality in employed U.S. adults aged 18-60 with diabetes.Lipids in health and disease · 2026Article
- Vitamin D and Sleep Disorders.Advances in experimental medicine and biology · 2026Review
- A pilot study investigating the effect of serum 25-hydroxyvitamin D on device-estimated sleep metrics in young black women: a single-arm open-label clinical trial.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Optimal sleep duration for cardiovascular prevention in Eastern Mediterranean populations: insights from a prospective cohort study.BMC cardiovascular disorders · 2025Article
- Association between vitamin D level and sleep quality in the elderly population: a prospective cohort study.Sleep & breathing = Schlaf & Atmung · 2025Article
- Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Serum 25-hydroxyvitamin D concentration is associated with device-estimated sleep metrics in healthy young and early middle-aged adults.Sleep advances : a journal of the Sleep Research Society · 2025Article
- Association of serum 25-hydroxyvitamin D with sleep disorders in individuals with prediabetes and diabetes: a prospective cohort study.Frontiers in endocrinology · 2025Article
- Current Aspects of Selected Factors to Modulate Brain Health and Sports Performance in Athletes.Nutrients · 2024Review
- Obstructive sleep apnea and vitamin D level: Has the dust settled?The clinical respiratory journal · 2024Review
- Association of Vitamin B12 Levels with Sleep Quality, Insomnia, and Sleepiness in Adult Primary Healthcare Users in Greece.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Association of Sleep Deprivation and the Risk of Developing Systemic Lupus Erythematosus Among Women.Arthritis care & research · 2023Article
- Rotating shift workers with vitamin D deficiency have a higher risk of obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Article
- Associations of serum 25-hydroxyvitamin D and subjective sleep measures in an arctic population: Insights from the population-based Tromsø Study.Sleep medicine: X · 2022Article
- Lower Serum Calcium Levels Associated with Disrupted Sleep and Rest-Activity Rhythm in Shift Workers.Nutrients · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
STUDY
objectivesTo determine the associations of 25-hydroxyvitamin D (25(OH)D) concentration with sleep continuity, quality, and symptoms, and to explore race/ethnic variation.
designCross-sectional study.
settingMulti-Ethnic Study of Atherosclerosis (MESA).
participantsThere were 1,721 adults. MEASUREMENTS AND
resultsSleep outcomes were measured by polysomnography, actigraphy, and questionnaires. Serum 25(OH)D concentration was expressed by clinical thresholds (< 20, 20-29, ≥ 30 ng/mL) and continuously. Using linear regression, we determined the associations between 25(OH)D concentration and sleep duration, efficiency, and symptoms, and assessed race/ethnic variation. Mean age was 68.2 ± 9.1 y, and 37.2% were white, 27.7% African American, 11.9% Chinese Americans, and 23.2% Hispanic. Mean 25(OH)D concentration was 25.4 ± 10.5 ng/mL. 25(OH)D deficient participants had the shortest sleep duration, lowest sleep efficiency, and highest sleepiness scores. After adjusting for demographics, obesity, and health habits, deficient individuals slept an average of 13.0 min (95% confidence interval, -22.8, -3.2) shorter than sufficient individuals. Race/ethnic-stratified analyses indicated that the strongest associations were in African Americans, in whom adjusted sleep duration was 25.6 ± 11.7 min shorter in deficient versus sufficient individuals (P = 0.04), and in Chinese Americans, adjusted apnea-hypopnea index (AHI) was 7.5 ± 3.3 events/h higher in deficient versus sufficient individuals.
conclusionOverall, there were modest associations between 25-hydroxyvitamin D (25(OH)D) concentration and sleep traits. However, race-stratified analyses suggested the association between 25(OH)D concentration and sleep traits varied by race/ethnicity. Vitamin D deficiency was most strongly associated with short sleep duration in African Americans and with elevated apnea-hypopnea index in Chinese Americans, suggesting that race/ethnicity may modify these associations.
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