ArticleJournal of natural products2015
Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta.
Article in Journal of natural products, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- The Extraordinary Benefit of Nature's Chemistry to Health, Society, and the Economy.Journal of natural products · 2025Review
- Last Decade Insights in Exploiting Marine Microorganisms as Sources of New Bioactive Natural Products.Marine drugs · 2025Review
- Multi-omics analysis of the correlation between surface microbiome and metabolome in Saccharina latissima (Laminariales, Phaeophyceae).FEMS microbiology ecology · 2025Article
- Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development.Frontiers in pharmacology · 2024Review
- Recent Advances of Marine Sponge-Associated Microorganisms as a Source of Commercially Viable Natural Products.Marine biotechnology (New York, N.Y.) · 2022Review
- Pharmacological Activities of Extracts and Compounds Isolated from Mediterranean Sponge Sources.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Recent Advances in Discovery of Lead Structures from Microbial Natural Products: Genomics- and Metabolomics-Guided Acceleration.Molecules (Basel, Switzerland) · 2021Review
- Insight into Unprecedented Diversity of Cyanopeptides in Eutrophic Ponds Using an MS/MS Networking Approach.Toxins · 2020Article
- Genome Mining as New Challenge in Natural Products Discovery.Marine drugs · 2020Review
- MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria.Marine drugs · 2018Article
- metaSPAdes: a new versatile metagenomic assembler.Genome research · 2017Article
- A Place to Call Home: An Analysis of the Bacterial Communities in Two Tethya rubra Samaai and Gibbons 2005 Populations in Algoa Bay, South Africa.Marine drugs · 2017Article
- Druggability and Binding Site Interaction Studies of Potential Metabolites Isolated from Marine Sponge Aurora globostellata against Human Epidermal Growth Factor Receptor-2.Bioinformation · 2017Article
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.Nature biotechnology · 2016Article
- Small Molecules in the Cone Snail Arsenal.Organic letters · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Spongosine (1), deoxyspongosine (2), spongothymidine (Ara T) (3), and spongouridine (Ara U) were isolated from the Caribbean sponge Tectitethya crypta and given the general name "spongonucleosides". Spongosine, a methoxyadenosine derivative, has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Investigations into unusual nucleoside production by T. crypta-associated microorganisms using mass spectrometric techniques have identified a spongosine-producing strain of Vibrio harveyi and several structurally related compounds from multiple strains.
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