Evidence map›Paper›PMID 25668349›Full record

ArticleJournal of hypertension2015

Associations between age, cohort, and urbanization with SBP and DBP in China: a population-based study across 18 years.

Samantha M Attard, Amy H Herring, Bing Zhang, Shufa Du, Barry M Popkin, Penny Gordon-Larsen

Abstract read
In one paragraph

Article in Journal of hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Prevalence of CVD Among Indian Adult Population: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Samantha M AttardaDepartment of Nutrition, Gillings School of Global Public Health bCarolina Population Center cDepartment of Biostatistics, Gillings School of Global Public Health, UNC-Chapel Hill, Chapel Hill, North Carolina, USA dNational Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Amy H Herring
Bing Zhang
Shufa Du
Barry M Popkin
Penny Gordon-Larsen
Chinese Center For Disease Control and Prevention · CNGTx (United States) · USUniversity of North Carolina at Chapel Hill · US

Funding

MONITORING SOCIAL CHANGE: HEALTH, REPRODUCTION, AGINGR01HD030880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 1994 to 2024
$27.0M
Carolina Population CenterR24HD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORGAN, SAMUEL PHILIP · 2005 to 2014
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Emergence of Cardiometabolic Risk Across the Lifecycle in ChinaR01HL108427 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2012 to 2015
$2.7M
Nutrition-Related NCD Prevention Training in ChinaD43TW009077 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI POPKIN, BARRY M · 2011 to 2015
$1.1M
Heterogeneity in Cardiometabolic Risk with Obesity: Who Is at Risk?R21DK089306 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GORDON-LARSEN, PENNY · 2010 to 2011
$405k
FIC NIH HHS D43 TW009077NHLBI NIH HHS R01 HL108427NHLBI NIH HHS R01-HL108427NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD030880NICHD NIH HHS R01-HD30880NICHD NIH HHS R24 HD050924NIDDK NIH HHS R21 DK089306NIDDK NIH HHS R21-DK089306
6 · The paper itself

Abstract

objectiveLittle is known about whether large-scale environmental changes, such as those seen with urbanization, are differentially associated with SBP versus DBP, and whether those changes vary by birth cohort.

methodsWe used data from the China Health and Nutrition Survey, a population-based cohort study of Chinese adults (n = 18 754 aged 18-70 years), seen a maximum of seven times from 1991 to 2009. We used hierarchical multivariable linear models to simultaneously estimate SBP and DBP as correlated outcomes over time, accounting for their physiologic, time-varying correlation. Main exposure variables were urbanicity, age, and birth cohort. Over 18 years of modernization, median SBP and DBP increased by 10 and 7 mmHg, respectively.

resultsOur hierarchical model results suggest greater temporal increases in SBP and particularly DBP at lower versus higher urbanicity. At the same chronological age, for a 10-year difference in birth cohort (i.e. born in 1980s versus 1970s), the adjusted mean DBP was approximately 3 mmHg higher for the later birth cohort (P < 0.001). Pulse pressure (calculated as model-predicted SBP minus DBP) was also higher at low versus high urbanicity.

conclusionsThese results suggest increased susceptibility of DBP (and thus peripheral vascular resistance) to environmental change, particularly in younger Chinese adults. Because DBP more strongly predicts cardiovascular disease risk in younger adulthood, hypertension-related health burden in China may increase over time.

Indexed as

UrbanizationAdolescentAdultAgedAge FactorsBlood PressureChinaCohort StudiesDiastoleFemaleHumansHypertensionLinear ModelsLongitudinal StudiesMaleMiddle Aged

Identifiers

PMID25668349
PMCPMC4412782
OpenAlexW2320118694

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.