Evidence map›Paper›PMID 25668266›Full record

ArticleJAMA2015

Echinacea for preventing and treating the common cold.

Marlies Karsch-Völk, Bruce Barrett, Klaus Linde

Abstract readComment
In one paragraph

Article in JAMA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Immune system evaluation of Echinacea Purpurea root extract in female Harlan Sprague Dawley (Hsd:Sprague Dawley SD) rats.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. A standardized extract ofPharmaceutical biology · 2023
    Article
  8. Article
  9. Evaluation of the efficacy ofDental research journal · 2022
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Motivations for Botanical Use by Socioeconomically Diverse, Urban Adults: Does Evidence Support Motivation?Journal of alternative and complementary medicine (New York, N.Y.) · 2017
    Article
  18. Natural Compounds as Occult Ototoxins? Ginkgo biloba Flavonoids Moderately Damage Lateral Line Hair Cells.Journal of the Association for Research in Otolaryngology : JARO · 2017
    Article
  19. Role ofJournal of family & community medicine
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Marlies Karsch-VölkInstitute of General Practice, Technische Universität München, Klinikum rechts der Isar, München, Germany.
Bruce BarrettDepartment of Family Medicine, University of Wisconsin-Madison, Madison.
Klaus LindeInstitute of General Practice, Technische Universität München, Klinikum rechts der Isar, München, Germany.
Klinikum rechts der Isar · DEUniversity of Wisconsin–Madison · US

Funding

Mentoring and research in patient-oriented medicineK24AT006543 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI BARRETT, BRUCE P · 2012 to 2016
$818k
NCCIH NIH HHS K24 AT006543
6 · The paper itself

Abstract

clinical questionAre Echinacea products associated with a reduced incidence and a shorter duration of common colds compared with placebo? BOTTOM LINE: Individual prophylaxis trials show no association with prevention of the common cold, but exploratory meta-analysis suggests that Echinacea products may be associated with a small reduction in cold incidence. In treatment trials, there was no association of Echinacea products with a shorter duration of colds.

Indexed as

EchinaceaPhytotherapyCommon ColdHumansPlant ExtractsPlant Extracts

Identifiers

PMID25668266
PMCPMC4367446
OpenAlexW3092678587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.