ArticlePediatrics2015
Successful treatment of an adolescent with Naegleria fowleri primary amebic meningoencephalitis.
Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.
- Fatal brain infection in early life: primary amoebic meningoencephalitis caused by Naegleria fowleri in neonates and infants.BMC infectious diseases · 2026Pooled it
- Neuroinvasive Free-Living Amoebae Pathogenesis, Neuroinflammation and Therapeutic Challenges.International journal of molecular sciences · 2026Review
- Cyclin-dependent kinase-inhibitor screening and structural analysis identify a CDK-like kinase candidate in Naegleria fowleri.Parasites & vectors · 2026Article
- Host factors, inflammatory markers, and clinical outcomes of Naegleria fowleri meningoencephalitis.Communications medicine · 2026Article
- Primary Amebic Meningoencephalitis Mimicking Acute Bacterial Meningitis: Survival Following Early Empirical Therapy.Cureus · 2026Article
- Global Review onInfectious disease reports · 2026Review
- Article
- CSF Leukocytes in Intracranial Infections: Diagnostic, Mechanistic, and Therapeutic Insights for Neurocritical Care.Cellular and molecular neurobiology · 2026Review
- Primary amoebic meningoencephalitis caused byFrontiers in pediatrics · 2026Article
- Potential Inhibitors of Human-Marine drugs · 2025Article
- Amoebas: the omnipotent organism and silent assassin.Molecular biology reports · 2025Review
- Detection and identification of Naegleria species along with Naegleria fowleri in the tap water samples.BMC medical genomics · 2025Article
- Article
- Encephalitis-causing free-living amoebic infections in children: A rare and fatal disease.Surgical neurology international · 2025Article
- Computational discovery of potential therapeutic agents against brain-eating amoeba (Naegleria fowleri).PloS one · 2025Article
- Therapeutic glycan-specific antibody binding mediates protection during primary amoebic meningoencephalitis.Infection and immunity · 2024Article
- Approaches for TargetingPathogens (Basel, Switzerland) · 2024Review
- Successful Treatment of Confirmed Naegleria fowleri Primary Amebic Meningoencephalitis.Emerging infectious diseases · 2024Article
- Noninvasive diagnostic biomarkers, genomic profiling, and advanced microscopic imaging in the early detection and characterization ofAnnals of medicine and surgery (2012) · 2024Review
- Miconazole-like Scaffold is a Promising Lead forJournal of medicinal chemistry · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.