ReviewGlobal heart2014
Antibiotic use and emerging resistance: how can resource-limited countries turn the tide?
Review in Global heart, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
124 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Antibiotic use in Brazilian hospitals in the 21st century: a systematic review.Revista da Sociedade Brasileira de Medicina Tropical · 2021Pooled it
- Non-malarial febrile illness: a systematic review of published aetiological studies and case reports from Africa, 1980-2015.BMC medicine · 2020Pooled it
- Utility of broad-spectrum antibiotics for diagnosing pulmonary tuberculosis in adults: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2020Pooled it
- Towards a global definition of responsible antibiotic use: results of an international multidisciplinary consensus procedure.The Journal of antimicrobial chemotherapy · 2018Pooled it
- How Health Policies Shape Antibiotic Use: A Nationwide Study of "Access"-Group Antibiotics Availability and Consumption in a Middle-Income Country: The Case of Kazakhstan.Antibiotics (Basel, Switzerland) · 2026Article
- Antibiotic prescribing practices and appropriateness of prescriptions in outpatient paediatric acute respiratory tract infections in Viet Nam.JAC-antimicrobial resistance · 2026Article
- Observational
- Clinico-epidemiological determinants for empirical antibiotic prescriptions in suspected urinary tract infection cases attending peripheral hospitals of West Bengal, India- a cross sectional analysis.Scientific reports · 2026Article
- Public knowledge and attitude toward antibiotic use and antimicrobial resistance in Riyadh region.Journal of family medicine and primary care · 2026Article
- Perspectives from Sri Lankan physicians on current approaches to diagnosing and managing lower respiratory tract infections.BMC research notes · 2026Article
- Antimicrobial resistance to colistin in neonates: epidemiological insights and public health implications in Nigeria - a mini review.Annals of medicine · 2025Review
- Portable Dynamic Laser Speckle Imaging for Rapid Antimicrobial Susceptibility Testing.ECS sensors plus · 2025Article
- Alkanna tinctoria extract-mediated biomass synthesis of Ag-ZnO nanoparticles: characterization, antimicrobial and antibiofilm activities.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Antimicrobial resistance awareness and food safety concerns among rural households in Zimbabwe.One health (Amsterdam, Netherlands) · 2025Article
- Diagnostic Underuse and Antimicrobial Resistance Patterns Among Hospitalized Children in a National Referral Hospital in Kenya: A Five-Year Retrospective Study.Antibiotics (Basel, Switzerland) · 2025Article
- Pattern and appropriateness of antibiotic therapy for acute respiratory tract infection among under-five children accessing care in a tertiary facility, Sokoto, Nigeria.BMJ paediatrics open · 2025Article
- Assessing patient-level risk factors for evidence-based early diagnosis of maternal sepsis.BMC pregnancy and childbirth · 2025Article
- The Definition, Prevalence, and Risk Factors of Augmented Renal Clearance in Adult Patients on Antimicrobial Therapy: A Scoping Review.Infectious diseases & clinical microbiology · 2025Article
- Antibiotic resistance in Helicobacter pylori: a genetic and physiological perspective.Gut pathogens · 2025Review
- Developing a clinical prediction model to modify empirical antibiotics for non-typhoidal Salmonella bloodstream infection in children under-five in the Democratic Republic of Congo.BMC infectious diseases · 2025Observational
64 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Antibiotic resistance is a global crisis driven by appropriate and inappropriate antibiotic use to treat human illness and promote animal growth. The antimicrobial resistance epidemic continues to spread due to the triple threat of unfettered access, minimal product regulation and oversight of antibiotic prescription, and lack of clinical diagnostic tools to support antibiotic de-escalation in low-resource settings. In high-resource settings, evidence-based strategies have improved the appropriateness of antibiotic use, limiting the spread of drug-resistant organisms and reducing hospital-associated infections, strategies which may also be effective to stop the spread of resistance in resource-poor countries. Current research and surveillance efforts on antimicrobial resistance and hospital-associated infections in low-resource settings are extremely limited and largely focused on intensive care units. Many challenges exist to improving antibiotic use and infection control in resource-limited settings, and turning the tide requires intensifying research and surveillance, antimicrobial stewardship, and developing new bedside diagnostic tools for bacterial infections and antimicrobial susceptibility.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.