Evidence map›Paper›PMID 25667184›Full record

ReviewGlobal heart2014

Global burden of influenza as a cause of cardiopulmonary morbidity and mortality.

William A Fischer, Michelle Gong, Satish Bhagwanjee, Jonathan Sevransky

Open access · hybridAbstract readReview
In one paragraph

Review in Global heart, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

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  10. HarnessingMaterials today. Bio · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

William A FischerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; The Center for Environmental Medicine, Asthma and Lung Biology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. Electronic address: William_Fischer@med.unc.edu.
Michelle GongAlbert Einstein College of Medicine, Bronx, NY, USA.
Satish BhagwanjeeDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.
Jonathan SevranskyDivision of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, GA, USA.
Albert Einstein College of Medicine · USEmory University · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
The Effect of Aging on LAIV Replication in Human Nasal Epithelial CellsR03AG045088 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISCHER, WILLIAM · 2013 to 2014
$152k
NCATS NIH HHS KL2 TR001109NCATS NIH HHS KL2TR001109NHLBI NIH HHS HL10871203NHLBI NIH HHS HL12299801NHLBI NIH HHS HL12511901NIA NIH HHS AG045088NIA NIH HHS R03 AG045088
6 · The paper itself

Abstract

Severe acute respiratory infections, including influenza, are a leading cause of cardiopulmonary morbidity and mortality worldwide. Until recently, the epidemiology of influenza was limited to resource-rich countries. Emerging epidemiological reports characterizing the 2009 H1N1 pandemic, however, suggest that influenza exerts an even greater toll in low-income, resource-constrained environments where it is the cause of 5% to 27% of all severe acute respiratory infections. The increased burden of disease in this setting is multifactorial and likely is the result of higher rates of comorbidities such as human immunodeficiency virus, decreased access to health care, including vaccinations and antiviral medications, and limited healthcare infrastructure, including oxygen therapy or critical care support. Improved global epidemiology of influenza is desperately needed to guide allocation of life-saving resources, including vaccines, antiviral medications, and direct the improvement of basic health care to mitigate the impact of influenza infection on the most vulnerable populations.

Indexed as

Cost of IllnessCardiovascular DiseasesGlobal HealthHumansInfluenza, HumanLung DiseasesMorbidity

Identifiers

PMID25667184
PMCPMC4327778
OpenAlexW2050732008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.