Evidence map›Paper›PMID 25667031›Full record

ReviewGastroenterology clinics of North America2015

Gastric arrhythmias in gastroparesis: low- and high-resolution mapping of gastric electrical activity.

Gregory O'Grady, Thomas L Abell

Open access · greenAbstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Gastric slow-wave morphology in health and disease.Digestive diseases and sciences · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. The Surgeon's Role in Gastric Electrical Stimulation Therapy for Gastroparesis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Review
  11. Enlightening the frontiers of neurogastroenterology through optogenetics.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Review
  12. Proteomics in gastroparesis: unique and overlapping protein signatures in diabetic and idiopathic gastroparesis.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Gregory O'GradyDepartment of Surgery, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Thomas L AbellDivision of Gastroenterology, GI Motility Clinic, University of Louisville, 220 Abraham Flexner Way, Suite 300, Louisville, KY 40202, USA. Electronic address: thomas.abell@louisville.edu.
University of Auckland · NZUniversity of Louisville · US

Funding

U of L Clinical Center to Investigate the Pathogenesis, Etiology, and Treatment of Gastroparesis through the NIDDK Gastroparesis ConsortiumU01DK074007 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI Thomas Lyman Abell · 2006 to 2026
$7.0M
Realistic models of gastrointestinal bioelectromagnetismR01DK064775 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHENG, LEO · 2004 to 2014
$2.6M
NIDDK NIH HHS R01 DK064775NIDDK NIH HHS R01 DK64775NIDDK NIH HHS U01 DK074007
6 · The paper itself

Abstract

Gastric arrhythmias occur in gastroparesis but their significance is debated. An improved understanding is currently emerging, including newly-defined histopathologic abnormalities in gastroparesis. In particular, the observation that interstitial cells of Cajal are depleted and injured provides mechanisms for arrhythmogenesis in gastroparesis. Electrogastrography has been the dominant clinical method of arrhythmia analysis, but is limited by summative nature, low signal quality, and incomplete sensitivity and specificity. Recently, high-resolution (HR; multi-electrode) mapping has emerged, providing superior spatial data on arrhythmic patterns and mechanisms. However, HR mapping is invasive, and low-resolution approaches are being assessed as bridging techniques until endoscopic mapping is achieved.

Indexed as

ElectromyographyGastric EmptyingGastroparesisHumansStomachElectrogastrographyInterstitial cells of CajalSlow waveTachygastria

Identifiers

PMID25667031
PMCPMC4323584
OpenAlexW116034875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.