Evidence map›Paper›PMID 25666987›Full record

ReviewNature reviews. Urology2015

Neural reconstruction methods of restoring bladder function.

Sandra M Gomez-Amaya, Mary F Barbe, William C de Groat, Justin M Brown, Gerald F Tuite, Jacques Corcos, Susan B Fecho, Alan S Braverman, Michael R Ruggieri

Abstract readReview
In one paragraph

Review in Nature reviews. Urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. [Application and progress of bio-derived materials in bladder regeneration and repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. [Expert consensus on diagnosis and treatment of spina bifida].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021
    Article
  11. Heterologous spinal cord transplantation in man.Surgical neurology international · 2021
    Article
  12. Article
  13. Review
  14. Review
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  16. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sandra M Gomez-AmayaDepartment of Anatomy and Cell Biology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, PA 19140, USA.
Mary F BarbeDepartment of Anatomy and Cell Biology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, PA 19140, USA.
William C de GroatDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, W1352 Thomas E. Starzl Biomedical Science Tower, Pittsburgh, PA 15261, USA.
Justin M BrownDivision of Neurosurgery, University of California San Diego School of Medicine, 200 West Arbor Drive, San Diego, CA 92103-8893, USA.
Gerald F TuitePediatric Neuroscience Centre, All Children's Hospital, 601 5th Street South, Department 7855, Suite 511, St Petersburg, FL 33701, USA.
Jacques CorcosDepartment of Surgery, Division of Urology, McGill University, 3755 Cote Ste-Catherine, Montreal, QC H3T 1E2, Canada.
Susan B FechoDepartment of Art, Barton College, 700 Vance Street NE, Wilson, NC 27893, USA.
Alan S BravermanDepartment of Anatomy and Cell Biology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, PA 19140, USA.
Michael R RuggieriDepartment of Anatomy and Cell Biology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, PA 19140, USA.

Funding

Bladder, Urethra and Anal Sphincter ReinnervationR01NS070267 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI BARBE, MARY F · 2010 to 2024
$8.2M
NINDS NIH HHS NS070267-S1NINDS NIH HHS R01 NS070267NINDS NIH HHS R01NS070267
6 · The paper itself

Abstract

During the past century, diverse studies have focused on the development of surgical strategies to restore function of a decentralized bladder after spinal cord or spinal root injury via repair of the original roots or by transferring new axonal sources. The techniques included end-to-end sacral root repairs, transfer of roots from other spinal segments to sacral roots, transfer of intercostal nerves to sacral roots, transfer of various somatic nerves to the pelvic or pudendal nerve, direct reinnervation of the detrusor muscle, or creation of an artificial reflex pathway between the skin and the bladder via the central nervous system. All of these surgical techniques have demonstrated specific strengths and limitations. The findings made to date already indicate appropriate patient populations for each procedure, but a comprehensive assessment of the effectiveness of each technique to restore urinary function after bladder decentralization is required to guide future research and potential clinical application.

Indexed as

HumansNeurosurgical ProceduresPeripheral NervesPlastic Surgery ProceduresPolyradiculopathySpinal Cord InjuriesSpinal Nerve RootsUrinary BladderUrinary Bladder, Neurogenic

Identifiers

PMID25666987
PMCPMC4324509

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.