Trial reportInternational journal of clinical pharmacy2015
Reduced length of stay in radical cystectomy patients with oral versus parenteral post-operative nutrition protocol.
Trial report in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06002269 (A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients: the BOOST Study
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Total parenteral nutrition versus early enteral nutrition after cystectomy: a meta-analysis of postoperative outcomes.International urology and nephrology · 2019Pooled it
- Offering Guidance and Learning to Prescribers to Initiate Parenteral Nutrition using a Validated Electronic Decision TREE (OLIVE TREE).Journal of medical systems · 2022Article
- Enhanced Recovery After Surgery and Radical Cystectomy: A Systematic Review and Meta-Analysis.Research and reports in urology · 2021Review
- Optimizing Nutritional Status in Patients Undergoing Radical Cystectomy: A Systematic Scoping Review.Bladder cancer (Amsterdam, Netherlands) · 2021Article
- Nutrition risk and assessment process in patients with bladder cancer undergoing radical cystectomy.Urologic oncology · 2020Review
- Optimal Delivery of Follow-Up Care After Radical Cystectomy for Bladder Cancer.Research and reports in urology · 2020Review
- Impact of an oral nutrition protocol in patients treated with elective radical cystectomy: a long term follow-up.International journal of clinical pharmacy · 2019Article
- Emerging Impact of Malnutrition on Surgical Patients: Literature Review and Potential Implications for Cystectomy in Bladder Cancer.The Journal of urology · 2017Review
- Impact of Perioperative Immunonutrition on Complications in Patients Undergoing Radical Cystectomy: A Retrospective Analysis.Integrative cancer therapiesArticle
Corrections and comments
- Erratum issuedErratum to: Reduced length of stay in radical cystectomy patients with oral versus parenteral post-operative nutrition protocol.2015 · Elodie, Beels [corrected to Beels, Elodie]; Ludo, Willems [corrected to Willems, Ludo]; Isabel, Spriet [corrected to Spriet, Isabel]
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Europe, parenteral nutrition is often used after radical cystectomy to avoid postoperative malnourishment. To the best of our knowledge, however, there is a paucity of data to conclude on the best modality for delivering nutritional support to this patient group.
objectiveThe parenteral nutrition policy was reconsidered and an oral nutrition protocol was implemented by the clinical pharmacist and evaluated in terms of length of stay, number and type of postoperative complications and parenteral nutrition avoided costs.
settingA prospective interventional non-randomized before-after study was conducted. Regular radical cystectomy patients presenting without preoperative contra-indications for enteral nutrition were eligible.
methodsPostoperatively, in the control group, the parenteral nutrition policy from the ward was applied. Parenteral nutrition was initiated systematically and continued until the patient was able to tolerate solid food. In the interventional group, an oral nutrition protocol was implemented. Parenteral nutrition could be initiated if oral intake remained insufficient after 5 days. Main outcome measure The primary end point was postoperative length of stay. Secondary endpoints included the number of patients in whom the oral nutrition protocol was implemented successfully, as well as the number and type of postoperative complications.
resultsA total of 94 eligible patients was assigned consecutively to the control (n = 48) and to the interventional group (n = 46). Baseline demographics were comparable. A significant reduction in median length of stay was associated with the oral nutrition protocol [18 days (IQR 15-22) in the control group vs. 14 days (IQR 13-18) in the interventional group (p < 0.001)]. In 40 out of 46 patients from the interventional group, the oral nutrition protocol was implemented successfully. The number and type of postoperative complications did not differ significantly. Implementing the oral nutrition protocol resulted in a direct parenteral nutrition infusion bag cost saving of approximately €512 and a reduction in hospitalization cost of €2,608 per patient.
conclusionThe findings of our study showed that an oral nutrition protocol, when compared to the systematic postoperative use of parenteral nutrition, was associated with a decreased length of stay and costs in a regular radical cystectomy patient population.
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