Evidence map›Paper›PMID 25666372›Full record

ArticleParasitology research2015

Synthesis and characterization of silver nanoparticles using Gmelina asiatica leaf extract against filariasis, dengue, and malaria vector mosquitoes.

Udaiyan Muthukumaran, Marimuthu Govindarajan, Mohan Rajeswary, S L Hoti

RetractedAbstract readRetracted Publication
PubMed Publisher
In one paragraph

Article in Parasitology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 99 citations in OpenAlex.

  1. Phytotherapeutic efficacy ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
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  12. Botanical insecticide-based nanosystems for the control of Aedes (Stegomyia) aegypti larvae.Environmental science and pollution research international · 2020
    Review
  13. Review
  14. Evaluation of Larvicidal Efficacy ofJournal of arthropod-borne diseases · 2020
    Article
  15. A facile and rapid method for green synthesis ofSaudi journal of biological sciences · 2019
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Udaiyan MuthukumaranUnit of Vector Control, Phytochemistry and Nanotechnology, Department of Zoology, Annamalai University, Annamalainagar, 608 002, Tamil Nadu, India.
Marimuthu Govindarajan
Mohan Rajeswary
S L Hoti
Annamalai University · INRegional Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquitoes are blood-feeding insects and serve as the most important vectors for spreading human diseases such as malaria, yellow fever, dengue fever, and filariasis. The continued use of synthetic insecticides has resulted in resistance in mosquitoes. Synthetic insecticides are toxic and affect the environment by contaminating soil, water, and air, and then natural products may be an alternative to synthetic insecticides because they are effective, biodegradable, eco-friendly, and safe to environment. Botanical origin may serve as suitable alternative biocontrol techniques in the future. The present study was carried out to establish the larvicidal potential of leaf extracts of Gmelina asiatica and synthesized silver nanoparticles using aqueous leaf extract against late third instar larvae of Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus. Larvae were exposed to varying concentrations of plant extracts and synthesized AgNPs for 24 h. The results were recorded from UV-visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and energy-dispersive X-ray spectroscopy analysis support the biosynthesis and characterization of AgNPs. The maximum efficacy was observed in synthesized AgNPs against the larvae of An. stephensi (lethal dose (LC₅₀) = 22.44 μg/mL; LC₉₀ 40.65 μg/mL), Ae. aegypti (LC₅₀ = 25.77 μg/mL; LC₉₀ 45.98 μg/mL), and C. quinquefasciatus (LC₅₀ = 27.83 μg/mL; LC₉₀ 48.92 μg/mL), respectively. No mortality was observed in the control. This is the first report on mosquito larvicidal activity of plant-synthesized nanoparticles. Thus, the use of G. asiatica to synthesize silver nanoparticles is a rapid, eco-friendly, and a single-step approach and the AgNps formed can be potential mosquito larvicidal agents.

Indexed as

AedesAnimalsAnophelesCulexDengueFilariasisInsecticidesLarvaMalariaMetal NanoparticlesPlant ExtractsPlant LeavesSilverInsecticidesPlant ExtractsSilver

Identifiers

PMID25666372
OpenAlexW2018352469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.