Evidence map›Paper›PMID 25666150›Full record

ArticleAntimicrobial agents and chemotherapy2015

First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae.

Chang-Wen Xu, An-Yun Zhang, Chun-Mei Yang, Yun Pan, Zhong-Bin Guan, Chang-Wei Lei, Lin-Yao Peng, Qing-Zhou Li, Hong-Ning Wang

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Phenotypic and Genotypic Characterization of a Highly VirulentTransboundary and emerging diseases · 2024
    Article
  3. A Small Multihost Plasmid CarryingFrontiers in veterinary science · 2022
    Article
  4. Article
  5. Characterization ofMicroorganisms · 2021
    Article
  6. Article
  7. Isolation and Detection ofIranian journal of medical sciences · 2017
    Article
  8. Colistin Resistance GeneAntimicrobial agents and chemotherapy · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Chang-Wen XuCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
An-Yun ZhangCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Chun-Mei YangCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Yun PanCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Zhong-Bin GuanCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Chang-Wei LeiCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Lin-Yao PengCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Qing-Zhou LiCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China.
Hong-Ning WangCollege of Life Sciences, Sichuan University; Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province; Key Laboratory of Bio-resources and Eco-environment, Ministry of Education; and 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, Sichuan, People's Republic of China whongning@163.com.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The macrolide resistance gene erm(T) was identified for the first time in a porcine Erysipelothrix rhusiopathiae isolate from swine in China. The novel 3,749-bp small plasmid pER29, which carries erm(T), had a G+C content of 31% and four distinct open reading frames. The presence of pER29 increased by at least 128-fold the MICs of clindamycin and erythromycin for E. rhusiopathiae. The fitness cost of pER29 could be responsible for the low frequency of erm(T) in E. rhusiopathiae.

Indexed as

AnimalsAnti-Bacterial AgentsClindamycinDrug Resistance, BacterialErysipelothrixErysipelothrix InfectionsErythromycinGenes, BacterialMacrolidesMicrobial Sensitivity TestsOpen Reading FramesPlasmidsSwineAnti-Bacterial AgentsClindamycinErythromycinMacrolides

Identifiers

PMID25666150
PMCPMC4356795
OpenAlexW2123120058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.