Evidence map›Paper›PMID 25666030›Full record

ArticleEuropean journal of clinical pharmacology2015

Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people.

Frank Moriarty, Kathleen Bennett, Tom Fahey, Rose Anne Kenny, Caitriona Cahir

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  15. Association between Potentially Inappropriate Medication Use and Chronic Diseases in the Elderly.International journal of environmental research and public health · 2019
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  19. The use of proton pump inhibitors among older adults with intellectual disability: A cross sectional observational study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Frank MoriartyHRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland, frankmoriarty@rcsi.ie.
Kathleen Bennett
Tom Fahey
Rose Anne Kenny
Caitriona Cahir
Royal College of Surgeons in Ireland · IESt. James's Hospital · IETrinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to compare the prevalence of potentially inappropriate medicines (PIMs) and potential prescribing omissions (PPOs) using several screening tools in an Irish community-dwelling older cohort, to assess if the prevalence changes over time and to determine factors associated with any change.

methodsThis is a prospective cohort study of participants aged ≥65 years in The Irish Longitudinal Study on Ageing (TILDA) with linked pharmacy claims data (n = 2051). PIM and PPO prevalence was measured in the year preceding participants' TILDA baseline interviews and in the year preceding their follow-up interviews using the Screening Tool for Older Persons' Prescriptions (STOPP), Beers criteria (2012), Assessing Care of Vulnerable Elders (ACOVE) indicators and the Screening Tool to Alert doctors to Right Treatment (START). Generalised estimating equations were used to determine factors associated with change in prevalence over time.

resultsDepending on the screening tool used, between 19.8% (ACOVE indicators) and 52.7% (STOPP) of participants received a PIM at baseline, and PPO prevalence ranged from 38.2% (START) to 44.8% (ACOVE indicators), while 36.7% of participants had both a PIM and PPO. Common criteria were aspirin for primary prevention (19.6%) and omission of calcium/vitamin D in osteoporosis (14.7%). Prevalence of PIMs and PPOs increased at follow-up (PIMs range 22-56.1%, PPOs range 40.5-49.3%), and this was associated with patient age, female sex, and numbers of medicines and chronic conditions.

conclusionsSub-optimal prescribing is common in older patients. Ongoing prescribing review to optimise care is important, particularly as patients get older, receive more medicines or develop more illnesses.

Indexed as

AgedDrug PrescriptionsFemaleHumansInappropriate PrescribingLongitudinal StudiesMaleMedical ErrorsPractice Patterns, Physicians'PrevalenceProspective StudiesResidence Characteristics

Identifiers

PMID25666030
PMCPMC4356885
OpenAlexW2148138940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.