ArticleInternational journal of environmental research and public health2015
Parity and risk of death from gallbladder cancer among a cohort of premenopausal parous women in Taiwan.
Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Between guidelines and reality; the complex decision-making of acute cholecystitis in pregnancy.Langenbeck's archives of surgery · 2025Article
- Influence of Sociodemographic and Anthropometric Factors on Gallbladder Volume in Pregnancy in a Tertiary Hospital in Nigeria.Oman medical journal · 2022Article
- Reproductive factors and gall-bladder cancer, and the effect of common genetic variants on these associations: a case-control study in India.International journal of epidemiology · 2022Article
- Tamoxifen inhibits cell proliferation by impaired glucose metabolism in gallbladder cancer.Journal of cellular and molecular medicine · 2020Article
- Parity Differently Affects the Breast Cancer Specific Survival from Ductal Carcinoma In Situ to Invasive Cancer: A Registry-Based Retrospective Study from Korea.Breast cancer : basic and clinical research · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little epidemiologic research has been done on the etiology of gallbladder cancer (GC). This cohort study was undertaken to examine whether there is an association between parity and risk of death from GC. The study cohort consisted of 1,292,462 women who had a first and singleton childbirth between 1 January 1978 and 31 December 1987. We tracked each woman from the time of their first childbirth to 31 December 2009, and their vital status was ascertained by linking records with the computerized mortality database. Cox proportional hazard regression models were used to estimate the hazard ratios (HR) of death from GC associated with parity. There were 257 GC deaths during 34,980,246 person-years of follow-up. The mortality rate of GC was 0.73 cases per 100,000 person-years. As compared with women who had given birth to only one child, the adjusted HR was 1.20 (95% CI = 0.79-1.83) for women who had two children, 1.47 (95% CI = 0.95-2.29) for women who had three children, and 1.68 (95% CI = 0.99-2.85) for women with four or more births. There was a significant increasing trend in the adjusted HRs for GC with increasing parity. The findings suggested that premenopausal women of higher parity may increase the risk of death from GC.
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