Evidence map›Paper›PMID 25664478›Full record

ArticleInternational journal of experimental pathology2015

Behaviour of four different B16 murine melanoma cell sublines: C57BL/6J skin.

Corina Danciu, Camelia Oprean, Dorina E Coricovac, Cioca Andreea, Anca Cimpean, Heinfried Radeke, Codruta Soica, Cristina Dehelean

Abstract readComparative Study
In one paragraph

Article in International journal of experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  18. Melanoma tumour vasculature heterogeneity: from mice models to human.Journal of cancer research and clinical oncology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Corina DanciuDepartment of Pharmacognosy, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.
Camelia OpreanDepartment of Pharmaceutical Chemistry, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.
Dorina E CoricovacDepartment of Toxicology, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.
Cioca AndreeaDepartment of Pathology, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Anca CimpeanDepartment of Microscopic Morphology/Histology, Angiogenesis Research Center, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.
Heinfried RadekePharmazentrum Frankfurt/Center for Drug Research, Development, and Safety, Clinic of J. W. Goethe University, Frankfurt, Germany.
Codruta SoicaDepartment of Pharmaceutical Chemistry, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.
Cristina DeheleanDepartment of Toxicology, University of Medicine and Pharmacy 'Victor Babes', Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplantable murine melanomas are well-established models for the study of experimental cancer therapies. The aim of this study was to explore the behaviour of four different B16 murine melanoma cell sublines after inoculation into C57BL/6J mice; and, more specifically to analyse skin changes, with respect to two specific parameters: clinical (tumour volume, melanin amount, erythema) and histological (H & E, S100, VEGF expression). Both non-invasive and invasive analysis showed that B164A5 is the most aggressive melanoma cell line for C57BL/6J's skin, followed by B16F10 and then by diminished aggressive growth pattern by the B16GMCSF and B16FLT3 cell lines.

Indexed as

Cell TransplantationAnimalsBiomarkers, TumorCell Line, TumorCell ProliferationDisease Models, AnimalFemaleMelanomaMiceMice, Inbred C57BLNeoplasm InvasivenessSkinSkin NeoplasmsVascular Endothelial Growth Factor ABiomarkers, TumorVascular Endothelial Growth Factor AB164A5B16F10B16FLT3B16GMCSFC57BL/6J

Identifiers

PMID25664478
PMCPMC4459798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.