Evidence map›Paper›PMID 25664340›Full record

Trial reportTheScientificWorldJournal2015

The effect of a 12-week moderate intensity interval training program on the antioxidant defense capability and lipid profile in men smoking cigarettes or hookah: a cohort study.

Abdessalem Koubaa, Moez Triki, Hajer Trabelsi, Hamza Baati, Zouhair Sahnoun, Ahmed Hakim

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in TheScientificWorldJournal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Exercise interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Abdessalem KoubaaLaboratory of Pharmacology, Sfax Medicine Faculty SMF, Avenue Majida Boulila, 3029 Sfax, Tunisia ; Laboratory of Cardio-Circulatory, Respiratory, and Hormonal Adaptations to Muscular Exercise, Ibn El Jazzar Medicine Faculty, Avenue Mohamed Karoui, 4002 Sousse, Tunisia.
Moez TrikiResearch Unit (EM2S), Sfax Institute of Sport and Physical Education, Airport Road, P.O. Box 384, 3000 Sfax, Tunisia.
Hajer TrabelsiLaboratory of Cardio-Circulatory, Respiratory, and Hormonal Adaptations to Muscular Exercise, Ibn El Jazzar Medicine Faculty, Avenue Mohamed Karoui, 4002 Sousse, Tunisia.
Hamza BaatiLaboratory of Cardio-Circulatory, Respiratory, and Hormonal Adaptations to Muscular Exercise, Ibn El Jazzar Medicine Faculty, Avenue Mohamed Karoui, 4002 Sousse, Tunisia.
Zouhair SahnounLaboratory of Pharmacology, Sfax Medicine Faculty SMF, Avenue Majida Boulila, 3029 Sfax, Tunisia.
Ahmed HakimLaboratory of Pharmacology, Sfax Medicine Faculty SMF, Avenue Majida Boulila, 3029 Sfax, Tunisia.
University of Sousse · TNInstitut Supérieur du Sport et de l’Éducation Physique de Sfax · TNJazz Pharmaceuticals (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the impact of interval training program on the antioxidant defense capability and lipid profile in men smoking cigarettes or hookah unable or unwilling to quit smoking.

methodsThirty-five participants performed an interval training (2 : 1 work : rest ratio) 3 times a week for 12 weeks at an intensity of 70% of VO2max. All subjects were subjected to a biochemical test session before and after the training program.

resultsThe increase of total antioxidant status (TAS), glutathione peroxidase (GPx), and α-tocopherol, is significant only for cigarette smokers (CS) and hookah smokers (HS) groups. The decrease of malondialdehyde (MDA) and the increase of glutathione reductase (GR) are more pronounced in smokers groups compared to those of nonsmokers (NS). Superoxide dismutase (SOD) increases in NS, CS, and HS groups by 10.1%, 19.5%, and 13.3%, respectively (P < 0.001). Likewise, a significant improvement of high-density lipoprotein cholesterol (HDL-C) and TC/HDL-C ratio was observed in CS and HS groups (P < 0.05).

conclusionAlthough the interval training program does not have a significant effect on blood lipid levels, it seems to be very beneficial in the defense and prevention programs of oxidative stress.

Indexed as

Exercise TherapyAdultalpha-TocopherolGlutathione PeroxidaseGlutathione ReductaseHumansLipidsMaleMalondialdehydeMiddle AgedOxidative StressSmokingSuperoxide Dismutasealpha-TocopherolGlutathione PeroxidaseGlutathione ReductaseLipidsMalondialdehydeSuperoxide Dismutase

Identifiers

PMID25664340
PMCPMC4310461
OpenAlexW2075514696

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.