ReviewMaxillofacial plastic and reconstructive surgery2015
Microvascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca.
Review in Maxillofacial plastic and reconstructive surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Insular infraorbital neurovascular pedicle labial salivary gland transplantation for the treatment of severe dry eye disease: an IDEAL stage 0, 1 and 2a study.BMJ surgery, interventions, & health technologies · 2025Article
- Salivary Gland Transplantation as a Promising Approach for Tear Film Restoration in Severe Dry Eye Disease.Journal of clinical medicine · 2024Review
- Impact of dry eye disease treatment on patient quality of life.Frontiers in medicine · 2024Review
- [Role and mechanism of muscarinic acetylcholine receptor in the regulation of submandibular gland secretion].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019Article
- Autonomic reinnervation and functional regeneration in autologous transplanted submandibular glands in patients with severe keratoconjunctivitis sicca.International journal of oral science · 2018Article
- Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands.Journal of molecular histology · 2017Article
- Free thyroid transfer: Short-term results of a novel procedure to prevent post-radiation hypothyroidism.Head & neck · 2017Article
- Muscarinic acetylcholine receptor-mediated tight junction opening is involved in epiphora in late phase of submandibular gland transplantation.Journal of molecular histology · 2017Article
- Botulinum toxin related research in maxillofacial plastic and reconstructive surgery.Maxillofacial plastic and reconstructive surgery · 2016Article
- S100 and p65 expression are increased in the masseter muscle after botulinum toxin-A injection.Maxillofacial plastic and reconstructive surgery · 2016Article
- An Experimental Study on Botulinum Toxin Type A for the Treatment of Excessive Secretion after Submandibular Gland Transplantation in Rabbits.Journal of ophthalmology · 2016Article
- Novel Local Chimeric Flap Based on Tunnelized Facial Artery Myomucosal Island Flap and Submandibular Gland Flap for Reconstructions After Oral Squamous Cell Carcinoma Surgery.The Journal of craniofacial surgeryArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dry eye syndrome is a relatively common disease of the tears and ocular surfaces that results in discomfort, visual disturbance, and tear film instability with possible damage to the ocular surfaces. Microvascular submandibular gland (SMG) transfer offers a surgical alternative for a permanent autologous substitution of tears using the basal secretion of a transplanted SMG. Long-term follow-up reveals that this technique is a lasting and effective solution for patients with severe dry eye syndrome. The uncomfortable symptoms were relieved, and the frequency of use of pharmaceutical tear substitutes was reduced. Objective examination showed significant improvement in tear film and some features of ocular surface such as breakup time of tear film and corneal staining. Patients may suffer from obstruction of Wharton's duct or epiphora after surgery. Activation of secretion-related receptors could improve the early hypofunction of the denervated SMG and prevent the duct obstruction. Reduction surgery, partial SMG transplantation, uses of atropine gel or Botulinum toxin A could be the choices of treatment for epiphora.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.