Evidence map›Paper›PMID 25664233›Full record

ArticleCurrent geriatrics reports2015

Colonization with Multi-Drug Resistant Organisms in Nursing Homes: Scope, Importance, and Management.

Marco Cassone, Lona Mody

Open access · greenAbstract read
In one paragraph

Article in Current geriatrics reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  14. Outcomes After Total Knee Arthroplasty in Patients With Autism: A Retrospective Database Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marco CassoneDivision of Geriatric and Palliative Care Medicine, University of Michigan Medical School, Ann Arbor, MI.
Lona ModyDivision of Geriatric and Palliative Care Medicine, University of Michigan Medical School, Ann Arbor, MI ; Geriatrics Research Education and Clinical Center (GRECC), Veteran Affairs Ann Arbor Healthcare System, 11-G GRECC, 2215 Fuller Rd., Ann Arbor, MI 48105, US.
University of Michigan–Ann Arbor · US

Funding

Pathway from Functional Disability to Antimicrobial Resistance in Nursing HomesR01AG041780 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MODY, LONA · 2013 to 2017
$1.8M
Targeted Infection Prevention (TIP) Program in Nursing HomesR01AG032298 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MODY, LONA · 2009 to 2013
$1.7M
Preventing Infections and Antimicrobial Resistance in the Aging Population: Translational Research and Training ProgramK24AG050685 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody · 2015 to 2026
$1.4M
NIA NIH HHS K24 AG050685NIA NIH HHS R01 AG032298NIA NIH HHS R01 AG041780
6 · The paper itself

Abstract

Bacterial infections are among the most common causes of morbidity and mortality in Nursing Homes (NH) and other long term care facilities. Multi-drug resistant organisms (MDROs) represent an ever-increasing share of causative agents of infection, and their prevalence in NHs is now just as high as in acute-care facilities, or even higher. Indeed, NHs are now considered a major reservoir of MDROs for the community at large. Asymptomatic colonization is usually a prerequisite to development of symptomatic infection. While progress has been made in defining epidemiology of MDROs in NHs, few studies have evaluated the role of changing healthcare delivery in introducing and further transmitting MDROs in this setting. Furthermore, the factors influencing the spread of colonization and the key prognostic indicators leading to symptomatic infections in the burgeoning short stay population need to be explored further. The difficulty of this task lies in the heterogeneity of NHs in terms of focus of care, organization and resources, and on the diversity among the many MDRO species encountered, which harbor different resistance genes and with a different prevalence depending on the geographic location, local antimicrobial pressure and residents risk factors such as use of indwelling devices, functional disability, wounds and other comorbidities. We present literature findings on the scope and importance of colonization as a pathway to infection with MDROs in NHs, underline important open questions that need further research, and discuss the strength of the evidence for current and proposed screening, prevention, and management interventions.

Indexed as

ColonizationGeriatricMRSAMulti-Drug ResistantNursing HomeVRE

Identifiers

PMID25664233
PMCPMC4317322
OpenAlexW1975995055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.