ArticleSpringerPlus2015
Association of ANCA associated vasculitis and rheumatoid arthritis: a lesser recognized overlap syndrome.
Article in SpringerPlus, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Evaluation of clinicopathological features of renal biopsies in non-lupus rheumatic diseases: a university hospital experience.Renal failure · 2026Article
- ANCA-Associated Vasculitis with Predominant Peripheral and Central Nervous System Involvement: A Case Report.Journal of inflammation research · 2026Article
- Rare case report: a man with rheumatoid arthritis developed membranous nephropathy and ANCA-associated vasculitis successively.BMC nephrology · 2025Article
- Case Report: Triple autoimmune overlap: rheumatoid arthritis, systemic lupus erythematosus, and hypereosinophilic asthma with systemic manifestations.Frontiers in immunology · 2025Article
- Psoriasis Increases the Risk of ANCA Associated Vasculitis: Insights from A Propensity Score-Matched Study.ImmunoTargets and therapy · 2025Article
- Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis.Current drug targets · 2025Review
- Co-existence of ANCA-associated vasculitides with immune-mediated diseases: a single-center observational study.Rheumatology international · 2024Observational
- The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population.RMD open · 2024Article
- False-Positive Myeloperoxidase-Antineutrophil Cytoplasmic Antibody in a Patient with Rheumatoid Arthritis.The American journal of case reports · 2023Article
- Tocilizumab Attenuates Anti-neutrophil Cytoplasmic Antibody-associated Nephritis Occurring during Abatacept and Adalimumab Therapy for Rheumatoid Arthritis.Internal medicine (Tokyo, Japan) · 2023Article
- Dual Anti-Glomerular Basement Membrane and Anti-Neutrophil Cytoplasmic Antibodies-Positive Rapidly Progressive Glomerulonephritis with Rheumatoid Arthritis and Sjogren's Syndrome: A Case Report and Literature Review.Journal of clinical medicine · 2022Article
- Genetics of ANCA-associated vasculitis: role in pathogenesis, classification and management.Nature reviews. Rheumatology · 2022Review
- [Arthritis and pulmonary cavities].Zeitschrift fur Rheumatologie · 2022Article
- Anti-neutrophil cytoplasmic antibody associated vasculitis in patients with rheumatoid arthritis.BMC nephrology · 2022Observational
- Analysis of rs1864182 and rs1864183 variants in ATG10 gene and antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese Guangxi population.Journal of clinical laboratory analysis · 2022Article
- Rare Overlap of Granulomatosis With Polyangiitis in a Patient With Rheumatoid Arthritis.Cureus · 2021Article
- Challenges in diagnosis of limited granulomatosis with polyangiitis.Rheumatology international · 2021Review
- Does withdrawal of immunosuppression in rheumatoid arthritis after SARS-CoV-2 infection increase the risk of vasculitis?BMJ case reports · 2021Article
- Rituximab used for simultaneous treatment of PR3-ANCA positive vasculitis associated with rheumatoid arthritis: A case report.Clinical case reports · 2020Article
- Patients with ANCA-Associated Glomerulonephritis and Connective Tissue Diseases: A Comparative Study from the Maine-Anjou AAV Registry.Journal of clinical medicine · 2019Article
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Abstract
backgroundANCA associated vasculitis (AAV) is an autoimmune disease with significant morbidity and mortality, in which diagnostic delay is associated with worse outcomes. AAV is rarely found in association with other immune mediated diseases. Early recognition of such overlaps enables more timely diagnosis and may impact on disease outcome. We reviewed cases of AAV in which there was an overlap with rheumatoid arthritis (RA).
methodsWe performed a retrospective analysis of our vasculitis database for patients who had a diagnosis of AAV and RA, and a literature search to find other reported cases of this overlap syndrome.
resultsWe found six subjects who had a diagnosis of RA and developed AAV at a median of 10.5 years (range 4-43 years) after the diagnosis of RA. They had been treated with a mean of 2 disease modifying drugs (0-4) and all had evidence of renal involvement with median creatinine of 227 μmol/l (range 128-700 μmol/l). Only one had a diagnosis of granulomatosis with polyangiitis, while the rest had a clinical diagnosis of microscopic polyangiitis. Half of the patients had positive rheumatoid factor (RhF) at the time of vasculitis diagnosis, three had MPO-ANCA, one PR3-ANCA, and two had ANCA-negative pauci-immune vasculitis. Additionally, we found 29 other cases reported of this overlap, which also most frequently presented with vasculitic renal manifestations, and were frequently RhF positive at the time of AAV diagnosis.
conclusionsAAV occurs in subjects with RA rarely, and often with significant delay from the first rheumatological manifestations. Renal involvement is common.
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