Evidence map›Paper›PMID 25664138›Full record

ArticleInternational journal of clinical and experimental medicine2014

Autoimmune thrombocytopenia: a complication of fludarabine therapy in the treatment of Waldenstrom's macroglobulinemia.

Yujie Jiang, Hongjuan Peng, Xin Cui, Ying Zhou, Dai Yuan, Xiaohui Sui, Lingyan Zhang, Hongzhi Xu

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yujie JiangDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Hongjuan PengInstitute of Shandong Medical Imaging, Shandong University Jinan, Shandong, China.
Xin CuiDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Ying ZhouDepartment of Radiology, No.4 Hospital of Jinan City Jinan, Shandong, China.
Dai YuanDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Xiaohui SuiDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Lingyan ZhangDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Hongzhi XuDepartment of Hematology, Shandong Provincial Hospital Affiliated to Shandong University Jinan, Shandong, China.
Shandong Provincial Hospital · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fludarabine is an effective purine analogue which has become extensive used in lymph proliferative malignancies. However, an increased incidence of autoimmune disorders including autoimmune hemolytic anemia (AHIA) and idiopathic thrombocytopenia (ITP) is reported with the use of fludarabine. The exact mechanism for fludarabine to exacerbate thrombocytopenia is not distinct. In our report, we describe a patient with WM developed a refractory, life-threatening and fludarabine-associated thrombocytopenia which could not be explained by the cytotoxic effects of fludarabine. Possible mechanisms of fludarabine on autoimmune disorders are discussed.

Indexed as

FludarabinethrombocytopeniaWaldenstrom’s macroglobulinemia

Identifiers

PMID25664138
PMCPMC4307585
OpenAlexW2398759230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.