ArticleInternational journal of clinical and experimental medicine2014
Relationship between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study.
Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Decreased Bone Mineral Density Is Associated with Subclinical Atherosclerosis in Asymptomatic Non-Diabetic Postmenopausal Women.Journal of clinical medicine · 2025Article
- Associations between bone mineral density and coronary artery calcification: a systematic review and meta-analysis.Therapeutic advances in chronic disease · 2022Article
- Early vascular ageing biomarkers in osteoporotic outpatients: a pilot study.Scientific reports · 2020Article
- Article
- The effects of the elastin polymorphisms on carotid intima-media thickness in women aged 30 - 70.Journal of exercise nutrition & biochemistry · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoporosis and atherosclerosis are two conditions that confer the major cause of mortality and morbidity in postmenopausal women. Several studies have suggested that these two conditions are negatively correlated by a common pathway. The aim of our study was to show a relationship between bone mineral density (BMD) and carotid intima media thickness (CIMT), as two factors that are directly related to osteoporosis and atherosclerosis respectively.
methodsThe study group consisted of 136 postmenopausal women that presented at the Radiology Clinic of our hospital for BMD measurements. The CIMT was measured using High Resolution B mode Ultrasonography; BMD was measured at the lumbar spine and femoral neck using Dual-energy X-Ray Absorptiometry.
resultsThe mean IMT value in osteoporotic women (0.7±0.1 mm) was significantly higher compared to non-osteoporotic women (0.6±0.1 mm, P < 0.001). A significant negative correlation was found between CIMT and the T score of lumbar spine (r=-0.35; P < 0.001) and femoral neck (r=-0.23, P < 0.001), as well as Z score of the lumbar spine (r=-0.27, P=0.004). No significant correlation was found between CIMT and Z score of the femoral neck.
conclusionOur study shows that bone mineral density and carotid intima media thickness are negatively correlated, thus showing a possible relationship between osteoporosis and atherosclerosis. However, more research is necessary to determine the pathway that connects these two conditions.
Indexed as
Identifiers
25664067PMC4307514W2335949290What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.