Evidence map›Paper›PMID 25664033›Full record

ArticleInternational journal of clinical and experimental medicine2014

Red blood cell distribution width: a potential maker estimating disease activity of ankylosing spondylitis.

You-Fan Peng, Qiong Zhang, Ling Cao, Yang Liu, Dan Chen, Yu-Kun Sun, Zhao-Xia Zhang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Mean platelet volume, red cell distribution width, platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios in patients with ankylosing spondylitis and their relationships with high-frequency hearing thresholds.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016
    Trial
  3. Article
  4. Review
  5. Can Complete Blood Count Picture Tell Us More About the Activity of Rheumatological Diseases?Clinical medicine insights. Arthritis and musculoskeletal disorders · 2022
    Article
  6. Red cell distribution width is associated with hearing impairment in chronic kidney disease population: a retrospective cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Article
  7. Red Cell Distribution Width in Rheumatoid arthritis.Mediterranean journal of rheumatology · 2018
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

You-Fan PengLaboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Qiong ZhangLaboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Ling CaoLaboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Yang LiuHemopathy Research Center, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Dan ChenDepartment of Rheumatology, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Yu-Kun SunDepartment of Radiology, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Zhao-Xia ZhangLaboratory Medicine Diagnostic Centre, The First Affiliated Hospital, Xin Jiang Medical University Xinjiang Urumqi, China.
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is a autoimmune disease, early and accurate detection is vital for effective treatment. Very recently, a large of novel laboratory index were found to diagnose AS. However, the correlation between red blood cell distribution width (RDW) and AS has been poorly discussed in previous study. Then, our aim was to focus on the association between RDW and AS. AS patients without drugs treatments and healthy individuals were incorporated in our study. Laboratory parameters including RDW tests were conducted consecutively on the entire cohort of AS patients and healthy individuals. AS patients with increased RDW showed significant difference compared to healthy individuals (13.66±0.77 vs. 12.77±0.47, P<0.01), similarly, difference of AS patients and heathy individuals stratified by sex was almost the same as that in two groups. Some significantly positive correlation were observed between RDW and CRP, ESR, IgG, BASDAI score in patients with AS (r=0.356, P=0.018; r=0.481, P=0.001; r=0.385, P=0.010; r=0.586, P<0.01), almost identical results were showed when AS patients was stratified by gender. Finally, receiver operating characteristic (ROC) curves of RDW levels to identify AS patients exhibited a statistically significant level (area under the curve of 0.853; sensitivity of 72.7%, specificity of 81.4%). The results suggested that increased RDW was associated with AS and may be used as a potential marker estimating disease activity of AS.

Indexed as

Ankylosing spondylitisBath AS disease activity indexC-reactive proteinerythrocyte sedimentation ratered blood cell distribution width

Identifiers

PMID25664033
PMCPMC4307480
OpenAlexW2306233907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.