Evidence map›Paper›PMID 25663920›Full record

ArticleOncology letters2015

Vertebral carcinomatosis eleven years after advanced gastric cancer resection: A case report.

Francesco Iovino, Michele Orditura, Pasquale Pio Auriemma, Francesca Romana Ciorra, Giovanni Giordano, Consiglia Orabona, Francesco Bara, Renato Sergio, Beatrice Savastano, Alessio Fabozzi and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Francesco IovinoIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Michele OrdituraDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Pasquale Pio AuriemmaIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Francesca Romana CiorraIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Giovanni GiordanoIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Consiglia OrabonaIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Francesco BaraIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Renato SergioIX Division of General Surgery, Department of Anaesthetic, Surgical and Emergency Sciences, Second University of Naples, Naples I-80131, Italy.
Beatrice SavastanoDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Alessio FabozziDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Maria Maddalena LaterzaDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Jole VentrigliaDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Angelica PetrilloDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Carminia Maria Della CorteDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
Ferdinando DE VitaDivision of Medical Oncology, 'F. Magrassi - A. Lanzara' Department of Clinical and Experimental Medicine, Second University of Naples School of Medicine, Naples I-80131, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastasis is an uncommon event in advanced gastric cancer patients and bone metastases are rarely detected as isolated lesions. However, eleven years after treatment for locally advanced gastric cancer, including total gastrectomy followed by adjuvant chemotherapy, a 49-year-old female was admitted to the IX Division of General Surgery of the Second University of Naples (Naples, Italy) exhibiting severe progressive neurological symptoms. Magnetic resonance imaging indicated vertebral abnormalities, with evidence of marrow infiltration in several vertebral bodies; however, a contrast-enhanced computed tomography scan did not detect disease progression to other sites. Biopsy of the soft tissue at the level of the second lumbar vertebra (L2) revealed a metastatic lesion derived from gastric mucinous adenocarcinoma. The patient was initially treated with radiotherapy directed to the L2-L4 vertebral bodies to control the pain. Subsequently, systemic chemotherapy according to a FOLFOX-4 (leucovorin, fluorouracil and oxaliplatin) regimen commenced. However, after eight cycles, pulmonary progression of the disease occurred. Thus, palliative care was administered and the patient succumbed one month later. The late relapse of gastric cancer in the current patient may be associated with the theory of tumour dormancy.

Indexed as

gastric cancertumour dormancyvertebral metastases

Identifiers

PMID25663920
PMCPMC4315078
OpenAlexW2145136973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.