Evidence map›Paper›PMID 25663913›Full record

ArticleOncology letters2015

Cell death pathway induced by resveratrol-bovine serum albumin nanoparticles in a human ovarian cell line.

Liyuan Guo, Yan Peng, Yulian Li, Jingping Yao, Guangmei Zhang, Jie Chen, Jing Wang, Lihua Sui

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Resveratrol-loaded nanomedicines for cancer applications.Cancer reports (Hoboken, N.J.) · 2021
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. NaOncology letters · 2017
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Liyuan GuoDepartment of Obstetrics and Gynecology, Third Affiliated Hospital, Harbin Medical University, Harbin 150081, P.R. China.
Yan PengDepartment of Health, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, P.R. China.
Yulian LiDepartment of Obstetrics and Gynecology, Third Affiliated Hospital, Harbin Medical University, Harbin 150081, P.R. China.
Jingping YaoDepartment of Health, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, P.R. China.
Guangmei ZhangDepartment of Health, First Affiliated Hospital, Harbin Medical University, Harbin 150001, P.R. China.
Jie ChenDepartment of Obstetrics and Gynecology, Third Affiliated Hospital, Harbin Medical University, Harbin 150081, P.R. China.
Jing WangDepartment of Obstetrics and Gynecology, Third Affiliated Hospital, Harbin Medical University, Harbin 150081, P.R. China.
Lihua SuiDepartment of Obstetrics and Gynecology, Third Affiliated Hospital, Harbin Medical University, Harbin 150081, P.R. China.
Harbin Medical University · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNThird Affiliated Hospital of Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol-bovine serum albumin nanoparticles (RES-BSANP) exhibit chemotherapeutic properties, which trigger apoptosis. The aim of the present study was to investigate the caspase-independent cell death pathway induced by RES-BSANP in human ovarian cancer SKOV3 cells and to analyze its mechanism. Morphological changes were observed by apoptotic body/cell nucleus DNA staining using inverted and fluorescence microscopy. The cell death pathway was determined by phosphatidylserine translocation. Western blot analysis was conducted to detect the activation of apoptosis-inducing factor (AIF), cytochrome

Indexed as

apoptosiscaspase-independentprogrammed cell deathresveratrol-bovine serum albumin nanoparticles

Identifiers

PMID25663913
PMCPMC4315083
OpenAlexW2091179247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.