ArticleOncology letters2015
Liriodenine induces the apoptosis of human laryngocarcinoma cells via the upregulation of p53 expression.
Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Apoptotic Potential of Glucomoringin Isothiocyanate (GMG-ITC) Isolated fromMolecules (Basel, Switzerland) · 2023Article
- POM121 is a novel marker for predicting the prognosis of laryngeal cancer.Histology and histopathology · 2020Article
- Liriodenine enhances radiosensitivity in esophageal cancer ECA-109 cells by inducing apoptosis and GOncology letters · 2018Article
- Induction chemotherapy in patients with resectable laryngeal cancer: A meta-analysis.Molecular and clinical oncology · 2018Article
- Effect of Hospital to Home nutrition management model on postoperative clinical outcomes of patients with laryngeal carcinoma.Oncology letters · 2017Article
- Anticancer effects of liriodenine on the cell growth and apoptosis of human breast cancer MCF-7 cells through the upregulation of p53 expression.Oncology letters · 2017Article
- Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms.Molecules (Basel, Switzerland) · 2017Review
- SKA1 is overexpressed in laryngocarcinoma and modulates cell growth via P53 signaling pathway.Cell cycle (Georgetown, Tex.)Article
Corrections and comments
- Retraction · 2025-03-10Concerns/Issues about Data · Duplication of Data · Euphemisms for Duplication · Euphemisms for Plagiarism · Investigation by Journal/Publisher · Investigation by Third Party · Plagiarism of Data · · See also: https://pubpeer.com/publications/70A6612FD0B65F5C6F279E82A9A42A
- Retracted
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laryngocarcinoma is one of the most aggressive cancers that affects the head and neck region. The survival rate of patients with laryngocarcinoma is low due to late metastases and the resistance of the disease to chemotherapy and radiotherapy. Liriodenine, an alkaloid extracted from a number of plant species, has demonstrated antitumor effects on multiple types of cancer. However, the effects of liriodenine upon laryngocarcinoma, and the underlying mechanisms, are yet to be elucidated. The present study therefore investigated the potential antitumor effects of liriodenine on HEp-2 human laryngocarcinoma cells
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.